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Integrative habitat analysis and multi-instance deep learning for predictive model of PD-1/PD-L1 immunotherapy efficacy in NSCLC patients: a dual-center retrospective study.
BMC medical imaging
Jul 17, 2025
BACKGROUND: PD-1/PD-L1 immunotherapy represents the primary treatment for advanced NSCLC patients; however, response rates to this therapy vary among individuals. This dual-center study aimed to integrate habitat radiomics and multi-instance deep lea...
Deep learning models for deriving optimised measures of fat and muscle mass from MRI.
Scientific reports
Jul 17, 2025
Fat and muscle mass are potential biomarkers of wellbeing and disease in oncology, but clinical measurement methods vary considerably. Here we evaluate the accuracy, precision and ability to track change for multiple deep learning (DL) models that qu...
Predicting postprandial glucose excursions to personalize dietary interventions for type-2 diabetes management.
Scientific reports
Jul 17, 2025
Elevated postprandial glucose levels present a global epidemic and a major challenge in type-2 diabetes (T2D) management. A key barrier to developing effective dietary interventions for T2D management is the wide inter-individual variation in glycemi...
Deep Learning-Based Precision Cropping of Eye Regions in Strabismus Photographs: Algorithm Development and Validation Study for Workflow Optimization.
Journal of medical Internet research
Jul 17, 2025
BACKGROUND: Traditional ocular gaze photograph preprocessing, relying on manual cropping and head tilt correction, is time-consuming and inconsistent, limiting artificial intelligence (AI) model development and clinical application.
Machine Learning Prediction of Financial Toxicity in Patients with Resected Lung Cancer.
Journal of the American College of Surgeons
Jul 16, 2025
BACKGROUND: Financial toxicity (FT) refers to the financial stress and detrimental impact on quality of life experienced by patients due to treatment cost. In patients with resected lung cancer (LC), we sought to identify those at risk of developing ...
Which explanations do clinicians prefer? A comparative evaluation of XAI understandability and actionability in predicting the need for hospitalization.
BMC medical informatics and decision making
Jul 16, 2025
BACKGROUND: This study aims to address the gap in understanding clinicians' attitudes toward explainable AI (XAI) methods applied to machine learning models using tabular data, commonly found in clinical settings. It specifically explores clinicians'...
Conditional GAN performs better than orthopedic surgeon in virtual reduction of femoral neck fracture.
BMC musculoskeletal disorders
Jul 16, 2025
OBJECTIVE: Satisfied reduction of fracture is hard to achieve. The purpose of this study is to develop a virtual fracture reduction technique using conditional GAN (Generative Adversarial Network), and evaluate its performance in simulating and guidi...
An end-to-end interpretable machine-learning-based framework for early-stage diagnosis of gallbladder cancer using multi-modality medical data.
BMC cancer
Jul 16, 2025
BACKGROUND: The accurate early-stage diagnosis of gallbladder cancer (GBC) is regarded as one of the major challenges in the field of oncology. However, few studies have focused on the comprehensive classification of GBC based on multiple modalities....
Image quality and radiation dose of reduced-dose abdominopelvic computed tomography (CT) with silver filter and deep learning reconstruction.
Scientific reports
Jul 16, 2025
To assess the image quality and radiation dose between reduced-dose CT with deep learning reconstruction (DLR) using SilverBeam filter and standard dose with iterative reconstruction (IR) in abdominopelvic CT. In total, 182 patients (mean age ± stand...
Machine learning to evaluate the effects of non-clinical social determinant features in predicting colorectal Cancer mortality in a medically underserved Appalachian population.
Scientific reports
Jul 16, 2025
Colorectal cancer (CRC) is the 2nd leading cause of cancer death in the United States (US). Rural Appalachia suffers the highest CRC incidence and mortality rates. There are several non-clinical health-related social determinant factors (SDOH) associ...
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