AIMC Topic: Middle Aged

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Machine learning identifies KRT8 dysregulation and endothelial remodeling in Moyamoya disease.

Scientific reports
Moyamoya disease (MMD) is a rare occlusive cerebrovascular disease, and its pathological mechanism remains unclear at present. The abnormal vascular remodeling may be involved in vascular endothelial cells. In this study, RNA seq was performed on the...

Deep learning-based video analysis for automatically detecting penetration and aspiration in videofluoroscopic swallowing study.

Scientific reports
The videofluoroscopic swallowing study (VFSS) is the gold standard for diagnosing dysphagia, but its interpretation is time-consuming and requires expertise. This study developed a deep learning model for automatically detecting penetration and aspir...

Cost-effectiveness analysis of robotic exoskeleton versus conventional physiotherapy for stroke rehabilitation in Singapore from a health system perspective.

BMJ open
OBJECTIVES: This study conducted a comprehensive probabilistic cost-effectiveness analysis comparing robotic exoskeleton therapy to conventional physiotherapy for stroke rehabilitation in Singapore, focusing on three patient groups categorised by the...

Identifying and characterising asthma subgroups at high risk of severe exacerbations using machine learning and longitudinal real-world data.

BMJ health & care informatics
OBJECTIVES: To identify and characterise distinct subgroups of patients with asthma with severe acute exacerbations (AEs) by using a multistep clustering methodology that combines supervised and unsupervised machine learning.

Quantitative Research on Digitalized Treatment Options for Older Adults With Mental Illness: Scoping Review.

JMIR mental health
BACKGROUND: Older adults with mental illness face specific physical and psychosocial challenges and inequities, reflected in limited access to advanced technology. This digital divide is alarming as mental health interventions increasingly depend on ...

Scalable Precision Psychiatry With an Objective Measure of Psychological Stress: Prospective Real-World Study.

Journal of medical Internet research
BACKGROUND: Before meaningful progress toward precision psychiatry is possible, objective (unbiased) assessment of patient mental well-being must be validated and adopted broadly.

External validation of a prediction model for disability and pain after lumbar disc herniation surgery: a prospective international registry-based cohort study.

Acta orthopaedica
BACKGROUND AND PURPOSE:  We aimed to externally validate machine learning models developed in Norway by evaluating their predictive outcome of disability and pain 12 months after lumbar disc herniation surgery in a Swedish and Danish cohort.

Performance of GPT-4 for automated prostate biopsy decision-making based on mpMRI: a multi-center evidence study.

Military Medical Research
BACKGROUND: Multiparametric magnetic resonance imaging (mpMRI) has significantly advanced prostate cancer (PCa) detection, yet decisions on invasive biopsy with moderate prostate imaging reporting and data system (PI-RADS) scores remain ambiguous.

Understanding the determinants of treated bed net use in Ethiopia: A machine learning classification approach using PMA Ethiopia 2023 survey data.

PloS one
INTRODUCTION: Malaria remains a significant public health challenge in Ethiopia, with over 7.3 million cases and 1,157 deaths reported between January 1 and October 20, 2024. Despite extensive distribution campaigns, 35% of insecticide-treated nets (...

Identification and validation of parthanatos-related genes in end-stage renal disease.

Renal failure
BACKGROUND: End-Stage Renal Disease (ESRD) is a severe chronic kidney disease with a rising global incidence, often accompanied by various complications, severely impacting patients' quality of life. Parthanatos plays a crucial role in the pathogenes...