AI Medical Compendium Topic:
Models, Biological

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Modeling Antibacterial Activity with Machine Learning and Fusion of Chemical Structure Information with Microorganism Metabolic Networks.

Journal of chemical information and modeling
Predicting the activity of new chemical compounds over pathogenic microorganisms with different metabolic reaction networks (MRN ) is an important goal due to the different susceptibility to antibiotics. The ChEMBL database contains >160 000 outcomes...

Rice Blast Disease Recognition Using a Deep Convolutional Neural Network.

Scientific reports
Rice disease recognition is crucial in automated rice disease diagnosis systems. At present, deep convolutional neural network (CNN) is generally considered the state-of-the-art solution in image recognition. In this paper, we propose a novel rice bl...

Transfer learning for predicting human skin sensitizers.

Archives of toxicology
Computational prioritization of chemicals for potential skin sensitization risks plays essential roles in the risk assessment of environmental chemicals and drug development. Given the huge number of chemicals for testing, computational methods enabl...

Machine learning models for early sepsis recognition in the neonatal intensive care unit using readily available electronic health record data.

PloS one
BACKGROUND: Rapid antibiotic administration is known to improve sepsis outcomes, however early diagnosis remains challenging due to complex presentation. Our objective was to develop a model using readily available electronic health record (EHR) data...

Comparison of linear model and artificial neural network using antler beam diameter and length of white-tailed deer (Odocoileus virginianus) dataset.

PloS one
Evaluation of harvest data remains one of the most important sources of information in the development of strategies to manage regional populations of white-tailed deer. While descriptive statistics and simple linear models are utilized extensively, ...

Machine learning models for predicting post-cystectomy recurrence and survival in bladder cancer patients.

PloS one
Currently in patients with bladder cancer, various clinical evaluations (imaging, operative findings at transurethral resection and radical cystectomy, pathology) are collectively used to determine disease status and prognosis, and recommend neoadjuv...

Predicting overall survival of patients with hepatocellular carcinoma using a three-category method based on DNA methylation and machine learning.

Journal of cellular and molecular medicine
Hepatocellular carcinoma (HCC) is closely associated with abnormal DNA methylation. In this study, we analyzed 450K methylation chip data from 377 HCC samples and 50 adjacent normal samples in the TCGA database. We screened 47,099 differentially meth...

Deep Neural Networks as Scientific Models.

Trends in cognitive sciences
Artificial deep neural networks (DNNs) initially inspired by the brain enable computers to solve cognitive tasks at which humans excel. In the absence of explanations for such cognitive phenomena, in turn cognitive scientists have started using DNNs ...

Noninvasive prediction of Blood Lactate through a machine learning-based approach.

Scientific reports
We hypothesized that blood lactate concentration([Lac]) is a function of cardiopulmonary variables, exercise intensity and some anthropometric elements during aerobic exercise. This investigation aimed to establish a mathematical model to estimate [L...

Application of adaptive-network-based fuzzy inference systems to the parameter optimization of a biochemical rule-based model.

Computers in biology and medicine
In this study, the binding of allergens to antibody-receptor complexes was investigated. This process is important in understanding the allergic response. A BioNetGen model that simulates this process, combined with a novel method for encoding steric...