AI Medical Compendium Topic

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Epistemic uncertainty quantification in deep learning classification by the Delta method.

Neural networks : the official journal of the International Neural Network Society
The Delta method is a classical procedure for quantifying epistemic uncertainty in statistical models, but its direct application to deep neural networks is prevented by the large number of parameters P. We propose a low cost approximation of the Del...

Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review.

BMJ (Clinical research ed.)
OBJECTIVE: To assess the methodological quality of studies on prediction models developed using machine learning techniques across all medical specialties.

Probabilistic generative modeling and reinforcement learning extract the intrinsic features of animal behavior.

Neural networks : the official journal of the International Neural Network Society
It is one of the ultimate goals of ethology to understand the generative process of animal behavior, and the ability to reproduce and control behavior is an important step in this field. However, it is not easy to achieve this goal in systems with co...

Spatial Prediction of COVID-19 in China Based on Machine Learning Algorithms and Geographically Weighted Regression.

Computational and mathematical methods in medicine
COVID-19 has swept through the world since December 2019 and caused a large number of patients and deaths. Spatial prediction on the spread of the epidemic is greatly important for disease control and management. In this study, we predicted the cumul...

Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.

PLoS computational biology
Most predictive models based on gene expression data do not leverage information related to gene splicing, despite the fact that splicing is a fundamental feature of eukaryotic gene expression. Cigarette smoking is an important environmental risk fac...

AIEpred: An Ensemble Predictive Model of Classifier Chain to Identify Anti-Inflammatory Peptides.

IEEE/ACM transactions on computational biology and bioinformatics
Anti-inflammatory peptides (AIEs) have recently emerged as promising therapeutic agent for treatment of various inflammatory diseases, such as rheumatoid arthritis and Alzheimer's disease. Therefore, detecting the correlation between amino acid seque...

Prediction Models for Agonists and Antagonists of Molecular Initiation Events for Toxicity Pathways Using an Improved Deep-Learning-Based Quantitative Structure-Activity Relationship System.

International journal of molecular sciences
In silico approaches have been studied intensively to assess the toxicological risk of various chemical compounds as alternatives to traditional in vivo animal tests. Among these approaches, quantitative structure-activity relationship (QSAR) analysi...

Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival.

International journal of molecular sciences
Bisphenols are important environmental pollutants that are extensively studied due to different detrimental effects, while the molecular mechanisms behind these effects are less well understood. Like other environmental pollutants, bisphenols are bei...

Forecasting care seekers satisfaction with telemedicine using machine learning and structural equation modeling.

PloS one
Many individuals visit rural telemedicine centres to obtain safe and effective health remedies for their physical and emotional illnesses. This study investigates the antecedents of patients' satisfaction relating to telemedicine adoption in rural pu...