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Models, Statistical

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AI-based analysis of fetal growth restriction in a prospective obstetric cohort quantifies compound risks for perinatal morbidity and mortality and identifies previously unrecognized high risk clinical scenarios.

BMC pregnancy and childbirth
BACKGROUND: Fetal growth restriction (FGR) is a leading risk factor for stillbirth, yet the diagnosis of FGR confers considerable prognostic uncertainty, as most infants with FGR do not experience any morbidity. Our objective was to use data from a l...

Prediction of mortality in heart failure by machine learning. Comparison with statistical modeling.

European journal of internal medicine
BACKGROUND: Assessing the relative performance of machine learning (ML) methods and conventional statistical methods in predicting prognosis in heart failure (HF) still remains a challenging research field.

Probabilistic and machine-learning methods for predicting local rates of transcription elongation from nascent RNA sequencing data.

Nucleic acids research
Rates of transcription elongation vary within and across eukaryotic gene bodies. Here, we introduce new methods for predicting elongation rates from nascent RNA sequencing data. First, we devise a probabilistic model that predicts nucleotide-specific...

Scale-independent solid fraction prediction in dry granulation process using a gray-box model integrating machine learning model and Johanson model.

International journal of pharmaceutics
We propose a novel approach for predicting the solid fraction after roller compaction processes. It is crucial to predict and control the solid fraction, as it has a significant impact on the product quality. The solid fraction can be theoretically p...

Leveraging deep learning for nonlinear shape representation in anatomically parameterized statistical shape models.

International journal of computer assisted radiology and surgery
PURPOSE: Statistical shape models (SSMs) are widely used for morphological assessment of anatomical structures. However, a key limitation is the need for a clear relationship between the model's shape coefficients and clinically relevant anatomical p...

Prediction models for treatment response in migraine: a systematic review and meta-analysis.

The journal of headache and pain
BACKGROUND: Migraine is a complex neurological disorder with significant clinical variability, posing challenges for effective management. Multiple treatments are available for migraine, but individual responses vary widely, making accurate predictio...

Classification and regression machine learning models for predicting mixed toxicity of carbamazepine and its transformation products.

Environmental research
Carbamazepine (CBZ) and its transformation products (TPs) often occur in aquatic environments in the form of mixtures, posing potential risks to ecosystems. However, establishing standardized protocols for synthesizing, isolating, and acquiring these...

Challenges for Predictive Modeling With Neural Network Techniques Using Error-Prone Dietary Intake Data.

Statistics in medicine
Dietary intake data are routinely drawn upon to explore diet-health relationships, and inform clinical practice and public health. However, these data are almost always subject to measurement error, distorting true diet-health relationships. Beyond m...

Estimating Average Treatment Effects With Support Vector Machines.

Statistics in medicine
Support vector machine (SVM) is one of the most popular classification algorithms in the machine learning literature. We demonstrate that SVM can be used to balance covariates and estimate average causal effects under the unconfoundedness assumption....

Developing clinical prognostic models to predict graft survival after renal transplantation: comparison of statistical and machine learning models.

BMC medical informatics and decision making
INTRODUCTION: Renal transplantation is a critical treatment for end-stage renal disease, but graft failure remains a significant concern. Accurate prediction of graft survival is crucial to identify high-risk patients. This study aimed to develop pro...