AIMC Topic: Molecular Imaging
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Analysis of live cell images: Methods, tools and opportunities.
Methods (San Diego, Calif.)
Feb 27, 2017
Advances in optical microscopy, biosensors and cell culturing technologies have transformed live cell imaging. Thanks to these advances live cell imaging plays an increasingly important role in basic biology research as well as at all stages of drug ...
An advanced MRI and MRSI data fusion scheme for enhancing unsupervised brain tumor differentiation.
Computers in biology and medicine
Dec 27, 2016
Proton Magnetic Resonance Spectroscopic Imaging (H MRSI) has shown great potential in tumor diagnosis since it provides localized biochemical information discriminating different tissue types, though it typically has low spatial resolution. Magnetic ...
The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo I-CLINDE SPECT Imaging: A Test-Retest Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Nov 10, 2016
I-CLINDE is a radiotracer developed for SPECT and targets the 18-kDa translocator protein (TSPO). TSPO is upregulated in glial cells and used as a measure of neuroinflammation in a variety of central nervous system diseases. The aim of this study was...
Aged, 80 and over
Bridged Bicyclo Compounds, Heterocyclic
Adult
Tissue Distribution
Sensitivity and Specificity
Male
Middle Aged
Radiopharmaceuticals
Genotype
Reference Values
Receptors, GABA
Female
Humans
Molecular Imaging
Reproducibility of Results
Biomarkers
Aged
Tomography, Emission-Computed, Single-Photon
Brain
An Inversion Scheme for Hybrid Fluorescence Molecular Tomography Using a Fuzzy Inference System.
IEEE transactions on medical imaging
Sep 1, 2015
The imaging performance of fluorescence molecular tomography (FMT) improves when information from the underlying anatomy is incorporated into the inversion scheme, in the form of priors. The requirement for incorporation of priors has recently driven...
Molecular Association Assay Systems for Imaging Protein-Protein Interactions in Mammalian Cells.
Biosensors
May 8, 2025
Molecular imaging probes play a pivotal role in assaying molecular events in various physiological systems. In this study, we demonstrate a new genre of bioluminescent probes for imaging protein-protein interactions (PPIs) in mammalian cells, named t...
SNMMI to Host Summits on Artificial Intelligence and Patient Access.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Feb 1, 2022
Taming the Complexity: Using Artificial Intelligence in a Cross-Disciplinary Innovative Platform to Redefine Molecular Imaging and Radiopharmaceutical Therapy.
PET clinics
Jan 1, 2022
Artificial Intelligence for Brain Molecular Imaging.
PET clinics
Jan 1, 2022
AI has been applied to brain molecular imaging for over 30 years. The past two decades, have seen explosive progress. AI applications span from operations processes such as attenuation correction and image generation, to disease diagnosis and predict...
Demystifying Medico-legal Challenges of Artificial Intelligence Applications in Molecular Imaging and Therapy.
PET clinics
Jan 1, 2022
Artificial Intelligence (AI) has been rapidly embraced by imaging fields and offers a variety of benefits in nuclear medicine; however, the biggest hurdles to AI in health care will likely not be technological but legal. What happens when an error oc...
Deep learning for in vivo near-infrared imaging.
Proceedings of the National Academy of Sciences of the United States of America
Jan 5, 2021
Detecting fluorescence in the second near-infrared window (NIR-II) up to ∼1,700 nm has emerged as a novel in vivo imaging modality with high spatial and temporal resolution through millimeter tissue depths. Imaging in the NIR-IIb window (1,500-1,700 ...
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