Ecotoxicology and environmental safety
Aug 1, 2025
Osteoporosis (OP) is a chronic progressive bone disease, and its occurrence and development under cadmium exposure remain unclear. This study aims to explore the role of cadmium exposure in the pathogenesis of OP through a comprehensive analysis of m...
Endometrial adenocarcinoma carries a bleak prognosis, and the molecular markers that evaluate the progression of endometrial adenocarcinoma to advanced stages remain uncertain. Cell-cell communication plays a crucial role in the tumor microenvironmen...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jul 15, 2025
Osteosarcoma (OS) is an aggressive bone cancer that mainly occurs in children and adolescents. OS patients are mainly treated with neoadjuvant chemotherapy and surgical resection. This treatment is effective for early osteosarcoma. However, the effec...
Cow's milk protein allergy (CMA) is one of the most common food allergies in children worldwide. However, it is still not well understood why certain children outgrow their CMA and others do not. While there is increasing evidence for a link of CMA w...
The analysis of high-dimensional microbiome multiomics datasets is crucial for understanding the complex interactions between microbial communities and host physiological states across health and disease conditions. Despite their importance, current ...
Spatial multi-omics technologies provide valuable data on gene expression from various omics in the same tissue section while preserving spatial information. However, deciphering spatial domains within spatial omics data remains challenging due to th...
Tumor-infiltrating lymphocytes (TILs) are capable of recognizing tumor antigens, impacting tumor prognosis, predicting the efficacy of neoadjuvant therapies, contributing to the development of new cell-based immunotherapies, studying the tumor immune...
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival of under 10 % despite current therapies. Aggressive tumor biology, a desmoplastic stroma that limits drug delivery and immune cell infiltra...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jun 30, 2025
Heterotopic ossification (HO) is a pathological process where bone forms in extraskeletal tissues, often occurring as a complication of tissue repair following injury. This condition can lead to movement limitations, pain, and functional impairment. ...
MOTIVATION: Advances in high throughput technologies enabled large access to various types of omics. Each omics provides a partial view of the underlying biological process. Integrating multiple omics layers would help have a more accurate diagnosis....
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