Journal of computational biology : a journal of computational molecular cell biology
Jun 26, 2025
Cancer is a disease that is both complex and diverse, and effective diagnosis and treatment require an accurate depiction of tumor subtypes. Traditional methods of cancer identification, which rely on clinical and histopathological criteria, have lim...
The lipophilic nature of 2-methylisoborneol (2-MIB), a prevalent off-flavor compound in aquatic systems, raises concerns about its bioaccumulation potential and metabolic interference in fish. Most studies have focused on removing this compound from ...
Ecotoxicology and environmental safety
Jun 21, 2025
This study applied network toxicology and multimodal biological approaches integrated with machine learning to systematically identify four TCS-IS-related genes, providing a comprehensive understanding of the pathophysiological relationship between t...
Gastric cancer (GC) ranks as the fifth most commonly diagnosed malignancy and the fourth leading cause of cancer-related mortality worldwide. The integration of machine learning in the analysis of GC metabolomics data for biomarker identification rem...
Ecotoxicology and environmental safety
Jun 18, 2025
Polyethylene terephthalate (PET), a polymer widely used in consumer products, has recently been implicated in cancer progression, though its mechanistic underpinnings remain elusive. This multidisciplinary study systematically investigates PET's carc...
Crop production has been regarded as the major goal of agricultural activities, but the rapidly growing population and climate change have become more complex in the agricultural systems. Abiotic stress greatly affects crop productivity globally; dev...
Artemisia argyi Folium (AAF) is a widely used functional aromatic medicinal plant with significant health, culinary, and therapeutic value. However, geographical variations in environmental factors notably affect its metabolite production, making com...
PURPOSE: Colorectal cancer (CRC) ranks third in global incidence and second in mortality, with rates increasing among younger populations. The enteric nervous system (ENS) is crucial for gastrointestinal function, and its dysfunction is associated wi...
Glioblastoma (GBM) is classified into subtypes according to the molecular expression profile; the proneural subtype has a relatively good prognosis, and the mesenchymal type is the most aggressive form with the worst prognosis. GBM undergoes proneura...
is a highly versatile and resilient pathogen that can infect different tissues and rapidly develop resistance to multiple drugs. Ceftazidime-avibactam (CZA) is an antibiotic often used to treat multidrug-resistant infections; however, the knowledge ...
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