AIMC Topic: Multiple Sclerosis
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Integrative transcriptomic analysis reveals oligodendrocyte lineage switching in multiple sclerosis.
Life science alliance
Aug 4, 2025
Multiple sclerosis (MS) is a chronic disease of the central nervous system. The occurrence of MS is a phased process while its cause is still unclear. Here, by combining white matter single-nucleus transcriptomic datasets from MS and control samples,...
PediMS: A Pediatric Multiple Sclerosis Lesion Segmentation Dataset.
Scientific data
Jul 10, 2025
Multiple Sclerosis (MS) is a chronic autoimmune disease that primarily affects the central nervous system and is predominantly diagnosed in adults, making pediatric cases rare and underrepresented in medical research. This paper introduces the first ...
Wristful thinking: exploring the effects of robotic rehabilitation and cross-education for persons with multiple sclerosis.
Journal of neuroengineering and rehabilitation
Jul 5, 2025
The goal of this work was to develop an adaptive rehabilitation technique using a haptic wrist robot that would induce cross-education to an untrained limb. Fourteen individuals with Multiple Sclerosis (MS) and eight non-affected adults completed an ...
Peripheral HLA-DRCD141 Classical Monocytes Predict Relapse Risk and Worsening in Multiple Sclerosis.
Neurology(R) neuroimmunology & neuroinflammation
Jul 3, 2025
BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS characterized by a heterogeneous disease trajectory, highlighting the need for biomarkers to predict disease activity. Current disease-monitorin...
Relevance of choroid plexus volumes in multiple sclerosis.
Fluids and barriers of the CNS
May 8, 2025
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Machine learning and clinical EEG data for multiple sclerosis: A systematic review.
Artificial intelligence in medicine
Apr 29, 2025
Multiple Sclerosis (MS) is a chronic neuroinflammatory disease of the Central Nervous System (CNS) in which the body's immune system attacks and destroys the myelin sheath that protects nerve fibers, leading to a wide range of debilitating symptoms a...
Radiomics-based analysis of choroid plexus abnormalities in neuromyelitis optica spectrum disorders and multiple sclerosis and their clinical implications.
Multiple sclerosis and related disorders
Apr 22, 2025
BACKGROUND: The choroid plexus (CP) is closely linked to inflammation in multiple sclerosis (MS). While the CP volume is enlarged in MS compared with healthy controls (HC), no such changes are observed in neuromyelitis optica spectrum disorder (NMOSD...
Monitoring multiple sclerosis: digital and fluid phase biomarkers.
Current opinion in neurology
Mar 28, 2025
PURPOSE OF REVIEW: Monitoring of disease activity and treatment response in multiple sclerosis (MS) currently relies on the integration of qualitative clinical and radiological data that is of limited predictive value. An array of quantitative digita...
Machine Learning Methods for Classifying Multiple Sclerosis and Alzheimer's Disease Using Genomic Data.
International journal of molecular sciences
Feb 27, 2025
Complex diseases pose challenges in prediction due to their multifactorial and polygenic nature. This study employed machine learning (ML) to analyze genomic data from the UK Biobank, aiming to predict the genomic predisposition to complex diseases l...
Artificial intelligence versus neurologists: A comparative study on multiple sclerosis expertise.
Clinical neurology and neurosurgery
Feb 20, 2025
INTRODUCTION: Multiple sclerosis (MS) is an autoimmune neurodegenerative disease affecting the central nervous system. MS diagnosis is complex, requiring magnetic resonance imaging and cerebrospinal fluid analysis due to the lack of definitive biomar...
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