AIMC Topic: Multiple Sclerosis
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Relevance of choroid plexus volumes in multiple sclerosis.
Fluids and barriers of the CNS
May 8, 2025
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Radiomics-based analysis of choroid plexus abnormalities in neuromyelitis optica spectrum disorders and multiple sclerosis and their clinical implications.
Multiple sclerosis and related disorders
Apr 22, 2025
BACKGROUND: The choroid plexus (CP) is closely linked to inflammation in multiple sclerosis (MS). While the CP volume is enlarged in MS compared with healthy controls (HC), no such changes are observed in neuromyelitis optica spectrum disorder (NMOSD...
Monitoring multiple sclerosis: digital and fluid phase biomarkers.
Current opinion in neurology
Mar 28, 2025
PURPOSE OF REVIEW: Monitoring of disease activity and treatment response in multiple sclerosis (MS) currently relies on the integration of qualitative clinical and radiological data that is of limited predictive value. An array of quantitative digita...
Machine Learning Methods for Classifying Multiple Sclerosis and Alzheimer's Disease Using Genomic Data.
International journal of molecular sciences
Feb 27, 2025
Complex diseases pose challenges in prediction due to their multifactorial and polygenic nature. This study employed machine learning (ML) to analyze genomic data from the UK Biobank, aiming to predict the genomic predisposition to complex diseases l...
Artificial intelligence versus neurologists: A comparative study on multiple sclerosis expertise.
Clinical neurology and neurosurgery
Feb 20, 2025
INTRODUCTION: Multiple sclerosis (MS) is an autoimmune neurodegenerative disease affecting the central nervous system. MS diagnosis is complex, requiring magnetic resonance imaging and cerebrospinal fluid analysis due to the lack of definitive biomar...
Artificial intelligence and science of patient input: a perspective from people with multiple sclerosis.
Frontiers in immunology
Feb 17, 2025
Artificial intelligence (AI) can play a vital role in achieving a shift towards predictive, preventive, and personalized medicine, provided we are guided by the science with and of patient input. Patient-reported outcome measures (PROMs) represent a ...
Deep learning-based prediction of autoimmune diseases.
Scientific reports
Feb 7, 2025
Autoimmune Diseases are a complex group of diseases caused by the immune system mistakenly attacking body tissues. Their etiology involves multiple factors such as genetics, environmental factors, and abnormalities in immune cells, making prediction ...
Identification of lipid metabolism-related gene markers and construction of a diagnostic model for multiple sclerosis: An integrated analysis by bioinformatics and machine learning.
Analytical biochemistry
Jan 22, 2025
BACKGROUND: Multiple sclerosis (MS) is an autoimmune inflammatory disorder that causes neurological disability. Dysregulated lipid metabolism contributes to the pathogenesis of MS. This study aimed to identify lipid metabolism-related gene markers an...
AI-based assessment of longitudinal multiple sclerosis MRI: Strengths and weaknesses in clinical practice.
European journal of radiology
Jan 18, 2025
OBJECTIVES: In Multiple Sclerosis (MS) cerebral MRI is essential for disease and treatment monitoring. For this purpose, software solutions are available to support the radiologist with image interpretation and reporting of follow up imaging. Aim of ...
Differentiation between multiple sclerosis and neuromyelitis optic spectrum disorders with multilevel fMRI features: A machine learning analysis.
Scientific reports
Jan 14, 2025
The conventional statistical approach for analyzing resting state functional MRI (rs-fMRI) data struggles to accurately distinguish between patients with multiple sclerosis (MS) and those with neuromyelitis optic spectrum disorders (NMOSD), highlight...
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