OBJECTIVES: To develop and validate an interpretable and generalized machine learning model using MRI for the individualized prediction of induction chemotherapy (ICT) response and survival in locoregionally advanced nasopharyngeal carcinoma (LANPC).
BACKGROUND: Ras-GTPase-activating protein (GAP)-binding protein 1 (G3BP1) emerges as a pivotal oncogenic gene across various malignancies, notably including nasopharyngeal carcinoma (NPC). The use of automated image analysis tools for immunohistochem...
The present study analyzed the impact of age on the causes of death (CODs) in patients with nasopharyngeal carcinoma (NPC) undergoing chemoradiotherapy (CRT) using machine learning approaches. A total of 2841 patients (1037 classified as older, ≥ 60 ...
International journal of radiation oncology, biology, physics
Dec 19, 2024
PURPOSE: To establish an artificial intelligence (AI)-empowered multistep integrated (MSI) radiation therapy (RT) workflow for patients with nasopharyngeal carcinoma (NPC) and evaluate its feasibility and clinical performance.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 5, 2024
PURPOSE: To develop and validate a prognostic and predictive model integrating deep learning MRI features and clinical information in patients with stage II nasopharyngeal carcinoma (NPC) to identify patients with a low risk of progression for whom i...
IEEE journal of biomedical and health informatics
Dec 5, 2024
Pathological examination of nasopharyngeal carcinoma (NPC) is an indispensable factor for diagnosis, guiding clinical treatment and judging prognosis. Traditional and fully supervised NPC diagnosis algorithms require manual delineation of regions of ...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Nov 22, 2024
Automating the segmentation of nasopharyngeal carcinoma (NPC) is crucial for therapeutic procedures but presents challenges given the hurdles in amassing extensively annotated datasets. Although previous studies have applied self-supervised learning ...
International journal of radiation oncology, biology, physics
Nov 16, 2024
PURPOSE: To develop a deep learning method exploiting active learning and source-free domain adaptation for gross tumor volume delineation in nasopharyngeal carcinoma (NPC), addressing the variability and inaccuracy when deploying segmentation models...
BACKGROUND: This study aimed to construct and assess a comprehensive model that integrates MRI-derived deep learning radiomics, functional imaging (fMRI), and clinical indicators to predict early efficacy of radiotherapy in nasopharyngeal carcinoma (...
Journal of imaging informatics in medicine
Oct 18, 2024
Radiotherapy is recognized as the major treatment of nasopharyngeal carcinoma. Rapid and accurate dose prediction can improve the efficiency of the treatment planning process and the quality of radiotherapy plans. Currently, deep learning-based metho...
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