Background Nasopharyngeal carcinoma (NPC) may be cured with radiation therapy. Tumor proximity to critical structures demands accuracy in tumor delineation to avoid toxicities from radiation therapy; however, tumor target contouring for head and neck...
Cancer communications (London, England)
Sep 25, 2018
BACKGROUND: Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for malignancy identification during biopsy is low, thus leading to delayed or missed diagnosis for nasopharyngeal mali...
More than 50% of cancer patients are treated with radiotherapy, either exclusively or in combination with other methods. The planning and delivery of radiotherapy treatment is a complex process, but can now be greatly facilitated by artificial intell...
BACKGROUND: According to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system, over 50% of patients with nasopharyngeal carcinoma (NPC) have N1 disease at initial diagnosis. However, patients with N1 NPC are relatively unde...
We aimed to identify optimal machine-learning methods for radiomics-based prediction of local failure and distant failure in advanced nasopharyngeal carcinoma (NPC). We enrolled 110 patients with advanced NPC. A total of 970 radiomic features were ex...
International journal of radiation oncology, biology, physics
Feb 12, 2016
PURPOSE: Intensity modulated radiation therapy (IMRT) is widely used to achieve a highly conformal dose and improve treatment outcome. However, plan quality and planning time are institute and planner dependent, and no standardized tool exists to rec...
Identifying patients at high risk of an elevated lymph node ratio (LNR) is critical for optimizing the management of nasopharyngeal carcinoma (NPC), as LNR, defined as the ratio of metastatic to examined lymph nodes, serves as a key prognostic indica...
Epstein-Barr Virus (EBV) is the first tumor virus discovered in humans, which is closely related to the occurrence of a variety of malignant tumors, especially Nasopharyngeal Carcinoma (NPC). Epstein-Barr Virus (EBV)-associated NPC accounts for appro...
Neural networks : the official journal of the International Neural Network Society
Sep 1, 2025
Nasopharyngeal carcinoma (NPC) is a malignant tumor that originates from the back of the nasal canal from above the soft palate to the upper larynx. Because the nasopharyngeal location is deeply hidden, it is often difficult for a single imaging mean...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Aug 1, 2025
PURPOSE: To develop a combined dosiomics and deep learning (DL) model for predicting radiation dermatitis (RD) of grade ≥ 2 in patients with nasopharyngeal carcinoma (NPC) after radiation therapy (RT) based on radiation dose distribution.
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