AIMC Topic: Neoplasm Grading

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Classifying tumour infiltrating lymphocytes in oral squamous cell carcinoma histopathology using joint learning framework.

Scientific reports
Oral squamous cell carcinoma (OSCC) is the most common form of oral cancer, with increasing global incidence and have poor prognosis. Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC gr...

Deep Learning Enabled Scoring of Pancreatic Neuroendocrine Tumors Based on Cancer Infiltration Patterns.

Endocrine pathology
Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms that include tumors with different histomorphologic characteristics that can be correlated to sub-categories with different prognoses. In addition to the WHO grading sc...

An interpretable multi-scale convolutional attention residual neural network for glioma grading with Raman spectroscopy.

Analytical methods : advancing methods and applications
Since the malignancy of gliomas varies with their grade, classifying gliomas of different grades can assist doctors in developing personalized surgical plans during surgery, thereby improving the prognosis. Raman spectroscopy is an optical method for...

Comparative analysis of deep learning and radiomic signatures for overall survival prediction in recurrent high-grade glioma treated with immunotherapy.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Radiomic analysis of quantitative features extracted from segmented medical images can be used for predictive modeling of prognosis in brain tumor patients. Manual segmentation of the tumor components is time-consuming and poses significa...

Endoscopic ultrasonography-based intratumoral and peritumoral machine learning ultrasomics model for predicting the pathological grading of pancreatic neuroendocrine tumors.

BMC medical imaging
OBJECTIVES: The objective is to develop and validate intratumoral and peritumoral ultrasomics models utilizing endoscopic ultrasonography (EUS) to predict pathological grading in pancreatic neuroendocrine tumors (PNETs).

Physical Color Calibration of Digital Pathology Scanners for Robust Artificial Intelligence-Assisted Cancer Diagnosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
The potential of artificial intelligence (AI) in digital pathology is limited by technical inconsistencies in the production of whole slide images (WSIs). This causes degraded AI performance and poses a challenge for widespread clinical application, ...

When multiple instance learning meets foundation models: Advancing histological whole slide image analysis.

Medical image analysis
Deep multiple instance learning (MIL) pipelines are the mainstream weakly supervised learning methodologies for whole slide image (WSI) classification. However, it remains unclear how these widely used approaches compare to each other, given the rece...

Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.

Nature communications
Pediatric low-grade gliomas (pLGGs) exhibit heterogeneous prognoses and variable responses to treatment, leading to tumor progression and adverse outcomes in cases where complete resection is unachievable. Early prediction of treatment responsiveness...

Cooperative multi-task learning and interpretable image biomarkers for glioma grading and molecular subtyping.

Medical image analysis
Deep learning methods have been widely used for various glioma predictions. However, they are usually task-specific, segmentation-dependent and lack of interpretable biomarkers. How to accurately predict the glioma histological grade and molecular su...

Interpretable machine learning model for predicting clinically significant prostate cancer: integrating intratumoral and peritumoral radiomics with clinical and metabolic features.

BMC medical imaging
BACKGROUND: To develop and validate an interpretable machine learning model based on intratumoral and peritumoral radiomics combined with clinicoradiological features and metabolic information from magnetic resonance spectroscopy (MRS), to predict cl...