AIMC Topic: Neoplasm Invasiveness

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A CT-based deep learning model for subsolid pulmonary nodules to distinguish minimally invasive adenocarcinoma and invasive adenocarcinoma.

European journal of radiology
OBJECTIVE: To develop and validate a deep learning nomogram (DLN) model constructed from non-contrast computed tomography (CT) images for discriminating minimally invasive adenocarcinoma (MIA) from invasive adenocarcinoma (IAC) in patients with subso...

Phenotype Discovery and Geographic Disparities of Late-Stage Breast Cancer Diagnosis across U.S. Counties: A Machine Learning Approach.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
BACKGROUND: Disparities in the stage at diagnosis for breast cancer have been independently associated with various contextual characteristics. Understanding which combinations of these characteristics indicate highest risk, and where they are locate...

Predicting microvascular invasion in hepatocellular carcinoma: a deep learning model validated across hospitals.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiological and/or radiomics features ...

Soft robotic constrictor for in vitro modeling of dynamic tissue compression.

Scientific reports
Here we present a microengineered soft-robotic in vitro platform developed by integrating a pneumatically regulated novel elastomeric actuator with primary culture of human cells. This system is capable of generating dynamic bending motion akin to th...

Deep Learning-based Recalibration of the CUETO and EORTC Prediction Tools for Recurrence and Progression of Non-muscle-invasive Bladder Cancer.

European urology oncology
Despite being standard tools for decision-making, the European Organisation for Research and Treatment of Cancer (EORTC), European Association of Urology (EAU), and Club Urologico Espanol de Tratamiento Oncologico (CUETO) risk groups provide moderate...

Deep learning-based classification of blue light cystoscopy imaging during transurethral resection of bladder tumors.

Scientific reports
Bladder cancer is one of the top 10 frequently occurring cancers and leads to most cancer deaths worldwide. Recently, blue light (BL) cystoscopy-based photodynamic diagnosis was introduced as a unique technology to enhance the detection of bladder ca...

Human-recognizable CT image features of subsolid lung nodules associated with diagnosis and classification by convolutional neural networks.

European radiology
OBJECTIVES: The interpretability of convolutional neural networks (CNNs) for classifying subsolid nodules (SSNs) is insufficient for clinicians. Our purpose was to develop CNN models to classify SSNs on CT images and to investigate image features ass...

Using deep learning to predict microvascular invasion in hepatocellular carcinoma based on dynamic contrast-enhanced MRI combined with clinical parameters.

Journal of cancer research and clinical oncology
PURPOSE: Microvascular invasion (MVI) is a critical determinant of the early recurrence and poor prognosis of patients with hepatocellular carcinoma (HCC). Prediction of MVI status is clinically significant for the decision of treatment strategies an...

Predicting cell invasion in breast tumor microenvironment from radiological imaging phenotypes.

BMC cancer
BACKGROUND: The abundance of immune and stromal cells in the tumor microenvironment (TME) is informative of levels of inflammation, angiogenesis, and desmoplasia. Radiomics, an approach of extracting quantitative features from radiological imaging to...

Whole-slide margin control through deep learning in Mohs micrographic surgery for basal cell carcinoma.

Experimental dermatology
BACKGROUND: Basal cell carcinoma (BCC) is the most common type of skin cancer with incidence rates rising each year. Mohs micrographic surgery (MMS) is most often chosen as treatment for BCC on the face for which each frozen section has to be histolo...