AIMC Topic: Neoplasms

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Large Language Model Applications for Health Information Extraction in Oncology: Scoping Review.

JMIR cancer
BACKGROUND: Natural language processing systems for data extraction from unstructured clinical text require expert-driven input for labeled annotations and model training. The natural language processing competency of large language models (LLM) can ...

Establishing Artificial Intelligence-Powered Virtual Tumor Board Meetings in Pakistan.

Cancer control : journal of the Moffitt Cancer Center
Equitable cancer care in low- and middle-income countries is crucial as mortality rates continue to rise. Artificial intelligence (AI)-powered Virtual Tumor Board Meetings (VTBMs) offer an innovative solution that facilitates real-time collaboration ...

Cancer Cell Line Classification Using Raman Spectroscopy of Cancer-Derived Exosomes and Machine Learning.

Analytical chemistry
Liquid biopsies are an emerging, noninvasive tool for cancer diagnostics, utilizing biological fluids for molecular profiling. Nevertheless, the current methods often lack the sensitivity and specificity necessary for early detection and real-time mo...

scMalignantFinder distinguishes malignant cells in single-cell and spatial transcriptomics by leveraging cancer signatures.

Communications biology
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for characterizing tumor heterogeneity, yet accurately identifying malignant cells remains challenging. Here, we propose scMalignantFinder, a machine learning tool specifically designed to dis...

SGCLMD: Signed graph-based contrastive learning model for predicting somatic mutation-drug association.

Computers in biology and medicine
Somatic mutations could influence critical cellular processes, leading to uncontrolled cell growth and tumor formation. Understanding the intricate interactions between somatic mutations and drugs was crucial for advancing our knowledge of the underl...

Multimodal multi-instance evidence fusion neural networks for cancer survival prediction.

Scientific reports
Accurate cancer survival prediction plays a crucial role in assisting clinicians in formulating treatment plans. Multimodal data, such as histopathological images, genomic data, and clinical information, provide complementary and comprehensive inform...

Development and validation of pan-cancer lesion segmentation AI-model for whole-body 18F-FDG PET/CT in diverse clinical cohorts.

Computers in biology and medicine
BACKGROUND: This study develops a deep learning-based automated lesion segmentation model for whole-body 3DF-fluorodeoxyglucose (FDG)-Position emission tomography (PET) with computed tomography (CT) images agnostic to disease location and site.

Pan-cancer analysis of CDC7 in human tumors: Integrative multi-omics insights and discovery of novel marine-based inhibitors through machine learning and computational approaches.

Computers in biology and medicine
Cancer remains a significant global health challenge, with the Cell Division Cycle 7 (CDC7) protein emerging as a potential therapeutic target due to its critical role in tumor proliferation, survival, and resistance. However, a comprehensive analysi...

The relationship between epigenetic biomarkers and the risk of diabetes and cancer: a machine learning modeling approach.

Frontiers in public health
INTRODUCTION: Epigenetic biomarkers are molecular indicators of epigenetic changes, and some studies have suggested that these biomarkers have predictive power for disease risk. This study aims to analyze the relationship between 30 epigenetic biomar...

Nanomaterial-Based Molecular Imaging in Cancer: Advances in Simulation and AI Integration.

Biomolecules
Nanomaterials represent an innovation in cancer imaging by offering enhanced contrast, improved targeting capabilities, and multifunctional imaging modalities. Recent advancements in material engineering have enabled the development of nanoparticles ...