Advances in experimental medicine and biology
39523270
Malignant glioma resection is often the first line of treatment in neuro-oncology. During glioma surgery, the discrimination of tumor's edges can be challenging at the infiltration zone, even by using surgical adjuncts such as fluorescence guidance (...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
39069201
The tissue diagnosis of adenocarcinoma and intraductal carcinoma of the prostate includes Gleason grading of tumor morphology on the hematoxylin and eosin stain and immunohistochemistry markers on the prostatic intraepithelial neoplasia-4 stain (CK5/...
Accurately distinguishing tumor cells from normal cells is a key issue in tumor diagnosis, evaluation, and treatment. Fluorescence-based immunohistochemistry as the standard method faces the inherent challenges of the heterogeneity of tumor cells and...
PURPOSE: To explore the contributions of fundus autofluorescence (FAF) topographic imaging features to the performance of convolutional neural network-based deep learning (DL) algorithms in predicting geographic atrophy (GA) growth rate.
SIGNIFICANCE: Oral cancer surgery requires accurate margin delineation to balance complete resection with post-operative functionality. Current fluorescence imaging systems provide two-dimensional margin assessment yet fail to quantify tumor depth p...
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues, leading to progressive organ dysfunction and failure. Congo red is the gold-standard chemical stain for visualizing amyloid deposits in tissue, showing birefringenc...
Multiphoton fluorescence microscopy excited with femtosecond pulses at high repetition rates, particularly in the range of 100's MHz to GHz, offers an alternative solution to suppress photoinduced damage to biological samples, for example, photobleac...
A non-destructive method for determining the color value of pelletized red peppers is crucial for pepper processing factories. This study aimed to investigate the potentiality of visible and fluorescence images for the determination of color value of...
Precise navigation within intricate biological systems is pivotal for comprehending cellular functions and diagnosing diseases. Fluorescent molecular probes, designed to target specific biological molecules, are indispensable tools for this endeavor....
Breast cancer poses a significant health threat to women, necessitating advancements in diagnostic technologies. Breast dynamic optical imaging (DOI) technology, recognized for its non-invasive and radiation-free properties, is extensively utilized f...