AIMC Topic: Optogenetics
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Analysis of the role of wind information for efficient chemical plume tracing based on optogenetic silkworm moth behavior.
Bioinspiration & biomimetics
May 31, 2019
Many animals use olfactory information to search for feeding areas and other individuals in real time and with high efficiency. We focus on the chemical plume tracing (CPT) ability of male silkworm moths and investigate an efficient CPT strategy for ...
Dissecting the Catecholamines: How New Approaches Will Facilitate the Distinction between Noradrenergic and Dopaminergic Systems.
ACS chemical neuroscience
Mar 28, 2019
To overcome the limitations of fast scan cyclic voltammetry (FSCV) to discriminate between catecholamines, we discuss new approaches to monitor the dynamics of these neurochemicals with high spatial, genetic, and temporal specificity.
A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters.
Nature chemical biology
Feb 26, 2018
We developed a new way to engineer complex proteins toward multidimensional specifications using a simple, yet scalable, directed evolution strategy. By robotically picking mammalian cells that were identified, under a microscope, as expressing prote...
Optogenetics in Silicon: A Neural Processor for Predicting Optically Active Neural Networks.
IEEE transactions on biomedical circuits and systems
Aug 17, 2016
We present a reconfigurable neural processor for real-time simulation and prediction of opto-neural behaviour. We combined a detailed Hodgkin-Huxley CA3 neuron integrated with a four-state Channelrhodopsin-2 (ChR2) model into reconfigurable silicon h...
Optogenetics Based Rat-Robot Control: Optical Stimulation Encodes "Stop" and "Escape" Commands.
Annals of biomedical engineering
Jan 8, 2015
Electric brain stimulation is frequently used in bio-robot control. However, one possible limitation of electric stimulation is the resultant wide range of influences that may lead to unexpected side-effects. Although there has been prior research do...
Treatment of neuropathic pain after brachial plexus injury by implantable wireless charging flexible micro-LED array.
Optics express
Jul 28, 2025
Total brachial plexus injuries (TBPI) caused by trauma often inflict unbearable pain on patients. However, there is still a lack of effective treatment strategies for these conditions. Optogenetics, as an emerging interdisciplinary field, can bridge ...
Metaplasticity and continual learning: mechanisms subserving brain computer interface proficiency.
Journal of neural engineering
May 23, 2025
Brain computer interfaces (BCIs) require substantial cognitive flexibility to optimize control performance. Remarkably, learning this control is rapid, suggesting it might be mediated by neuroplasticity mechanisms operating on very short time scales....
Toward a living soft microrobot through optogenetic locomotion control of .
Science robotics
Jun 30, 2021
Learning from the locomotion of natural organisms is one of the most effective strategies for designing microrobots. However, the development of bioinspired microrobots is still challenging because of technical bottlenecks such as design and seamless...
Phototactic guidance of a tissue-engineered soft-robotic ray.
Science (New York, N.Y.)
Jul 8, 2016
Inspired by the relatively simple morphological blueprint provided by batoid fish such as stingrays and skates, we created a biohybrid system that enables an artificial animal--a tissue-engineered ray--to swim and phototactically follow a light cue. ...
Mapping Sub-Second Structure in Mouse Behavior.
Neuron
Dec 16, 2015
Complex animal behaviors are likely built from simpler modules, but their systematic identification in mammals remains a significant challenge. Here we use depth imaging to show that 3D mouse pose dynamics are structured at the sub-second timescale. ...
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