AIMC Topic: Core Binding Factor Alpha 1 Subunit

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Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.

Current osteoporosis reports May 24, 2025
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci associated with bone mineral density (BMD) and fracture risk. However, disparities persist due to the underreprese...
Asian People White People Core Binding Factor Alpha 1 Subunit African People Low Density Lipoprotein Receptor-Related Protein-5 Osteoporotic Fractures Gene-Environment Interaction Genome-Wide Association Study Osteoporosis Genetic Predisposition to Disease Genomics Machine Learning Bone Density Humans
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Machine learning identifies activation of RUNX/AP-1 as drivers of mesenchymal and fibrotic regulatory programs in gastric cancer.

Genome research Jun 25, 2024
Gastric cancer (GC) is the fifth most common cancer worldwide and is a heterogeneous disease. Among GC subtypes, the mesenchymal phenotype (Mes-like) is more invasive than the epithelial phenotype (Epi-like). Although gene expression of the epithelia...
DNA Copy Number Variations Core Binding Factor Alpha 1 Subunit Gene Expression Regulation, Neoplastic Transcription Factor AP-1 Core Binding Factor Alpha 2 Subunit Fibrosis Epithelial-Mesenchymal Transition Machine Learning Cell Line, Tumor Stomach Neoplasms Humans
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Predictive value of preoperative Fried Frailty Phenotype assessment and serum biomarkers on the prognosis of elderly patients with femoral neck fracture under general anesthesia within 3 months after surgery.

Turkish journal of medical sciences Dec 11, 2023
BACKGROUND/AIM: Femoral neck fracture (FNF) seriously impact the health of the elderly and affect their long-term quality of life of the patients. This study aimed to determine whether combining the preoperative Fried Frailty Phenotype (FFP) with ser...
Receptor, Fibroblast Growth Factor, Type 3 Male Anesthesia, General Middle Aged Aged, 80 and over Femoral Neck Fractures Phenotype Core Binding Factor Alpha 1 Subunit Predictive Value of Tests Prognosis Aged Frailty Female Biomarkers Humans
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Comparative analysis of weighted gene co-expression networks in human and mouse.

PloS one Nov 21, 2017
The application of complex network modeling to analyze large co-expression data sets has gained traction during the last decade. In particular, the use of the weighted gene co-expression network analysis framework has allowed an unbiased and systems-...
Retinoic Acid Receptor alpha Sequence Homology Gene Expression Profiling Animals Mice Gene Regulatory Networks Humans Tissue Distribution Homeodomain Proteins Gene Ontology Gene Expression Regulation Genetic Association Studies Core Binding Factor Alpha 1 Subunit Forkhead Transcription Factors
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