AIMC Topic: Ovarian Neoplasms

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Integrative Multi-Omics Analysis Reveals Molecular Subtypes of Ovarian Cancer and Constructs Prognostic Models.

Journal of immunotherapy (Hagerstown, Md. : 1997)
Ovarian cancer (OV) remains the most lethal gynecological malignancy. The aim of this study was to identify molecular subtypes of OV through integrative multi-omics analysis and construct machine learning-based prognostic models for predicting the ef...

CNRein: an evolution-aware deep reinforcement learning algorithm for single-cell DNA copy number calling.

Genome biology
Low-pass single-cell DNA sequencing technologies and algorithmic advancements have enabled haplotype-specific copy number calling on thousands of cells within tumors. However, measurement uncertainty may result in spurious CNAs inconsistent with real...

AI-driven patient support: Evaluating the effectiveness of ChatGPT-4 in addressing queries about ovarian cancer compared with healthcare professionals in gynecologic oncology.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: Artificial intelligence (AI) chatbots, such as ChatGPT-4, allow a user to ask questions on an interactive level. This study evaluated the correctness and completeness of responses to questions about ovarian cancer from a GPT-4 chatbot, LilyB...

Multiomics evaluation and machine learning optimize molecular classification, prediction of prognosis and immunotherapy response for ovarian cancer.

Pathology, research and practice
BACKGROUND: Ovarian cancer (OC), owing to its substantial heterogeneity and high invasiveness, has historically been devoid of precise, individualized treatment options. This study aimed to establish integrated consensus subtypes of OC using differen...

Explainable AI-based feature importance analysis for ovarian cancer classification with ensemble methods.

Frontiers in public health
INTRODUCTION: Ovarian Cancer (OC) is one of the leading causes of cancer deaths among women. Despite recent advances in the medical field, such as surgery, chemotherapy, and radiotherapy interventions, there are only marginal improvements in the diag...

AI-Derived Blood Biomarkers for Ovarian Cancer Diagnosis: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: Emerging evidence underscores the potential application of artificial intelligence (AI) in discovering noninvasive blood biomarkers. However, the diagnostic value of AI-derived blood biomarkers for ovarian cancer (OC) remains inconsistent...

Deep learning-based analysis of gross features for ovarian epithelial tumors classification: A tool to assist pathologists for frozen section sampling.

Human pathology
Computational pathology has primarily focused on analyzing tissue slides, neglecting the valuable information contained in gross images. To bridge this gap, we proposed a novel approach leveraging the Swin Transformer architecture to develop a Swin-T...

Ovarian masses suggested for MRI examination: assessment of deep learning models based on non-contrast-enhanced MRI sequences for predicting malignancy.

Abdominal radiology (New York)
PURPOSE: We aims to assessed and compare four deep learning(DL) models using non-contrast-enhanced magnetic resonance imaging(MRI) to differentiate benign from malignant ovarian tumors, considering diagnostic efficacy and associated development costs...

Identification of prognostic subtypes and the role of FXYD6 in ovarian cancer through multi-omics clustering.

Frontiers in immunology
BACKGROUND: Ovarian cancer (OC), as a malignant tumor that seriously endangers the lives and health of women, is renowned for its complex tumor heterogeneity. Multi-omics analysis, as an effective method for distinguishing tumor heterogeneity, can mo...

Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures.

Journal of translational medicine
BACKGROUND: Prior studies have elucidated that alterations in gut microbiota are associated with a spectrum of tumors and metabolic disorders. However, the diagnostic value of gut microbiota in epithelial ovarian cancer remains insufficiently investi...