AIMC Topic: Pancreatitis
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Therapeutic potential of Da Cheng Qi Decoction and its ingredients in regulating ferroptosis via the NOX2-GPX4 signaling pathway to alleviate and predict severe acute pancreatitis.
Cellular signalling
Mar 11, 2025
OBJECTIVE: This study aimed to elucidate the protective effects of Da Cheng Qi Decoction (DCQD) on severe acute pancreatitis (SAP) by targeting ferroptosis in pancreatic acinar cells and to establish a predictive signature and nomogram for acute panc...
Machine learning for the rElapse risk eValuation in acute biliary pancreatitis: The deep learning MINERVA study protocol.
World journal of emergency surgery : WJES
Mar 3, 2025
BACKGROUND: Mild acute biliary pancreatitis (MABP) presents significant clinical and economic challenges due to its potential for relapse. Current guidelines advocate for early cholecystectomy (EC) during the same hospital admission to prevent recurr...
Explainable machine learning model for predicting acute pancreatitis mortality in the intensive care unit.
BMC gastroenterology
Mar 3, 2025
BACKGROUND: Current prediction models are suboptimal for determining mortality risk in patients with acute pancreatitis (AP); this might be improved by using a machine learning (ML) model. In this study, we aimed to construct an explainable ML model ...
Predicting the risk of acute kidney injury in patients with acute pancreatitis complicated by sepsis using a stacked ensemble machine learning model: a retrospective study based on the MIMIC database.
BMJ open
Feb 26, 2025
OBJECTIVE: This study developed and validated a stacked ensemble machine learning model to predict the risk of acute kidney injury in patients with acute pancreatitis complicated by sepsis.
A systematic review of machine learning-based prognostic models for acute pancreatitis: Towards improving methods and reporting quality.
PLoS medicine
Feb 24, 2025
BACKGROUND: An accurate prognostic tool is essential to aid clinical decision-making (e.g., patient triage) and to advance personalized medicine. However, such a prognostic tool is lacking for acute pancreatitis (AP). Increasingly machine learning (M...
Resveratrol in animal models of pancreatitis and pancreatic cancer: A systematic review with machine learning.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feb 23, 2025
BACKGROUND: Resveratrol (RES), a common type of plant polyphenols, has demonstrated promising therapeutic efficacy and safety in animal models of pancreatitis and pancreatic cancer. However, a comprehensive analysis of these data is currently unavail...
Impact of Sepsis Onset Timing on All-Cause Mortality in Acute Pancreatitis: A Multicenter Retrospective Cohort Study.
Journal of intensive care medicine
Feb 18, 2025
BackgroundSepsis complicates acute pancreatitis (AP), increasing mortality risk. Few studies have examined how sepsis and its onset timing affect mortality in AP. This study evaluates the association between sepsis occurrence and all-cause mortality ...
Development of an interpretable machine learning model based on CT radiomics for the prediction of post acute pancreatitis diabetes mellitus.
Scientific reports
Jan 15, 2025
This study sought to establish and validate an interpretable CT radiomics-based machine learning model capable of predicting post-acute pancreatitis diabetes mellitus (PPDM-A), providing clinicians with an effective predictive tool to aid patient man...
Interpretable prediction of 30-day mortality in patients with acute pancreatitis based on machine learning and SHAP.
BMC medical informatics and decision making
Nov 5, 2024
BACKGROUND: Severe acute pancreatitis (SAP) can be fatal if left unrecognized and untreated. The purpose was to develop a machine learning (ML) model for predicting the 30-day all-cause mortality risk in SAP patients and to explain the most important...
Association Between Body Composition Measured by Artificial Intelligence and Long-Term Sequelae After Acute Pancreatitis.
Digestive diseases and sciences
Oct 22, 2024
BACKGROUND/OBJECTIVES: The clinical utility of body composition in the development of complications of acute pancreatitis (AP) remains unclear. We aimed to describe the associations between body composition and the recurrence of AP.
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