AIMC Topic: Patient Selection

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Epilepsy surgery candidate identification with artificial intelligence: An implementation study.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
BACKGROUND: To (a) evaluate the effect of a machine learning algorithm in the identification of patients suitable for epilepsy surgery evaluation, and (b) examine the performance of a large language model (LLM) in the collation of key pieces of infor...

Redefining prostate cancer care: innovations and future directions in active surveillance.

Current opinion in urology
PURPOSE OF REVIEW: This review provides a critical analysis of recent advancements in active surveillance (AS), emphasizing updates from major international guidelines and their implications for clinical practice.

Recruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial.

Journal of medical Internet research
BACKGROUND: With increasing adoption of remote clinical trials in digital mental health, identifying cost-effective and time-efficient recruitment methodologies is crucial for the success of such trials. Evidence on whether web-based recruitment meth...

ImpACT Project: Improving Access to Clinical Trials in Victoria, an Artificial Intelligence-Based Approach.

JCO clinical cancer informatics
PURPOSE: Enhancing the speed and efficiency of clinical trial recruitment is a key objective across international health systems. This study aimed to use artificial intelligence (AI) applied in the Victorian Cancer Registry (VCR), a population-based ...

Metastatic Versus Localized Disease as Inclusion Criteria That Can Be Automatically Extracted From Randomized Controlled Trials Using Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: Extracting inclusion and exclusion criteria in a structured, automated fashion remains a challenge to developing better search functionalities or automating systematic reviews of randomized controlled trials in oncology. The question "Did th...

Structural analysis and intelligent classification of clinical trial eligibility criteria based on deep learning and medical text mining.

Journal of biomedical informatics
OBJECTIVE: To enhance the efficiency, quality, and innovation capability of clinical trials, this paper introduces a novel model called CTEC-AC (Clinical Trial Eligibility Criteria Automatic Classification), aimed at structuring clinical trial eligib...

Harnessing explainable artificial intelligence for patient-to-clinical-trial matching: A proof-of-concept pilot study using phase I oncology trials.

PloS one
This study aims to develop explainable AI methods for matching patients with phase 1 oncology clinical trials using Natural Language Processing (NLP) techniques to address challenges in patient recruitment for improved efficiency in drug development....

Learning to match patients to clinical trials using large language models.

Journal of biomedical informatics
OBJECTIVE: This study investigates the use of Large Language Models (LLMs) for matching patients to clinical trials (CTs) within an information retrieval pipeline. Our objective is to enhance the process of patient-trial matching by leveraging the se...