AIMC Topic: Positron-Emission Tomography

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Translating amyloid PET of different radiotracers by a deep generative model for interchangeability.

NeuroImage
It is challenging to compare amyloid PET images obtained with different radiotracers. Here, we introduce a new approach to improve the interchangeability of amyloid PET acquired with different radiotracers through image-level translation. Deep genera...

Deep learning-based metal artefact reduction in PET/CT imaging.

European radiology
OBJECTIVES: The susceptibility of CT imaging to metallic objects gives rise to strong streak artefacts and skewed information about the attenuation medium around the metallic implants. This metal-induced artefact in CT images leads to inaccurate atte...

Cerebral blood flow measurements with O-water PET using a non-invasive machine-learning-derived arterial input function.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Cerebral blood flow (CBF) can be measured with dynamic positron emission tomography (PET) of O-labeled water by using tracer kinetic modelling. However, for quantification of regional CBF, an arterial input function (AIF), obtained from arterial bloo...

Deep learning-based T1-enhanced selection of linear attenuation coefficients (DL-TESLA) for PET/MR attenuation correction in dementia neuroimaging.

Magnetic resonance in medicine
PURPOSE: The accuracy of existing PET/MR attenuation correction (AC) has been limited by a lack of correlation between MR signal and tissue electron density. Based on our finding that longitudinal relaxation rate, or R , is associated with CT Hounsfi...

Sub-2 mm depth of interaction localization in PET detectors with prismatoid light guide arrays and single-ended readout using convolutional neural networks.

Medical physics
PURPOSE: Depth of interaction (DOI) readout in PET imaging has been researched in efforts to mitigate parallax error, which would enable the development of small diameter, high-resolution PET scanners. However, DOI PET has not yet been commercialized...

Automatic rat brain image segmentation using triple cascaded convolutional neural networks in a clinical PET/MR.

Physics in medicine and biology
The purpose of this work was to develop and evaluate a deep learning approach for automatic rat brain image segmentation of magnetic resonance imaging (MRI) images in a clinical PET/MR, providing a useful tool for analyzing studies of the pathology a...

Artificial intelligence enables whole-body positron emission tomography scans with minimal radiation exposure.

European journal of nuclear medicine and molecular imaging
PURPOSE: To generate diagnostic F-FDG PET images of pediatric cancer patients from ultra-low-dose F-FDG PET input images, using a novel artificial intelligence (AI) algorithm.

Integrating Multiomics Information in Deep Learning Architectures for Joint Actuarial Outcome Prediction in Non-Small Cell Lung Cancer Patients After Radiation Therapy.

International journal of radiation oncology, biology, physics
PURPOSE: Novel actuarial deep learning neural network (ADNN) architectures are proposed for joint prediction of radiation therapy outcomes-radiation pneumonitis (RP) and local control (LC)-in stage III non-small cell lung cancer (NSCLC) patients. Unl...

Denoising non-steady state dynamic PET data using a feed-forward neural network.

Physics in medicine and biology
The quality of reconstructed dynamic PET images, as well as the statistical reliability of the estimated pharmacokinetic parameters is often compromised by high levels of statistical noise, particularly at the voxel level. Many denoising strategies h...