AIMC Topic: Positron-Emission Tomography

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Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospective observational study.

Alzheimer's research & therapy
BACKGROUND: Intracerebral amyloid β (Aβ) accumulation is considered the initial observable event in the pathological process of Alzheimer's disease (AD). Efficient screening for amyloid pathology is critical for identifying patients for early treatme...

Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma.

European journal of nuclear medicine and molecular imaging
PURPOSE: Radiomics-based machine learning (ML) models of amino acid positron emission tomography (PET) images have shown efficiency in glioma prediction tasks. However, their clinical impact on physician interpretation remains limited. This study inv...

Clinical validation of artificial intelligence-based single-subject morphometry without normative reference database.

Journal of Alzheimer's disease : JAD
BACKGROUND: Single-subject voxel-based morphometry (VBM) is a powerful technique for reader-independent detection of brain atrophy in structural magnetic resonance imaging (MRI) to support the (differential) diagnosis and staging of neurodegenerative...

Explainable PET-Based Habitat and Peritumoral Machine Learning Model for Predicting Progression-free Survival in Clinical Stage IA Pure-Solid Non-small Cell Lung Cancer: A Two-center Study.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop and validate machine learning (ML) models utilizing positron emission tomography (PET)-habitat of the tumor and its peritumoral microenvironment to predict progression-free survival (PFS) in patie...

The Value of Machine Learning-based Radiomics Model Characterized by PET Imaging with Ga-FAPI in Assessing Microvascular Invasion of Hepatocellular Carcinoma.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop a radiomics model characterized by Ga-fibroblast activation protein inhibitors (FAPI) positron emission tomography (PET) imaging to predict microvascular invasion (MVI) of hepatocellular carcinoma...

A multi-view learning approach with diffusion model to synthesize FDG PET from MRI T1WI for diagnosis of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: This study presents a novel multi-view learning approach for machine learning (ML)-based Alzheimer's disease (AD) diagnosis.

Self-supervised neural network for Patlak-based parametric imaging in dynamic [F]FDG total-body PET.

European journal of nuclear medicine and molecular imaging
PURPOSE: The objective of this study is to generate reliable K parametric images from a shortened [F]FDG total-body PET for clinical applications using a self-supervised neural network algorithm.

3D full-dose brain-PET volume recovery from low-dose data through deep learning: quantitative assessment and clinical evaluation.

European radiology
OBJECTIVES: Low-dose (LD) PET imaging would lead to reduced image quality and diagnostic efficacy. We propose a deep learning (DL) method to reduce radiotracer dosage for PET studies while maintaining diagnostic quality.

A deep learning method for the recovery of standard-dose imaging quality from ultra-low-dose PET on wavelet domain.

European journal of nuclear medicine and molecular imaging
PURPOSE: Recent development in positron emission tomography (PET) dramatically increased the effective sensitivity by increasing the geometric coverage leading to total-body PET imaging. This encouraging breakthrough brings the hope of ultra-low dose...

Multi-scale multimodal deep learning framework for Alzheimer's disease diagnosis.

Computers in biology and medicine
Multimodal neuroimaging data, including magnetic resonance imaging (MRI) and positron emission tomography (PET), provides complementary information about the brain that can aid in Alzheimer's disease (AD) diagnosis. However, most existing deep learni...