AIMC Topic: Precision Medicine

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Modeling engagement in long-term, in-home socially assistive robot interventions for children with autism spectrum disorders.

Science robotics
Socially assistive robotics (SAR) has great potential to provide accessible, affordable, and personalized therapeutic interventions for children with autism spectrum disorders (ASD). However, human-robot interaction (HRI) methods are still limited in...

Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice.

Schizophrenia bulletin
In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of psychosis in the hope that these could aid the prediction of onset and clinical outcome. Despite advancements in the field, neuro...

Evaluation of clinical impact of pharmacogenomics knowledge involved in CPIC guidelines on Chinese pediatric patients.

Pharmacogenomics
To evaluate the clinical benefits of implementing pharmacogenomics testing for Chinese pediatric patients.   Based on the drug-gene interactions involved in the Clinical Pharmacogenetics Implementation Consortium guidelines, whole-genome sequencing ...

DeepCOP: deep learning-based approach to predict gene regulating effects of small molecules.

Bioinformatics (Oxford, England)
MOTIVATION: Recent advances in the areas of bioinformatics and chemogenomics are poised to accelerate the discovery of small molecule regulators of cell development. Combining large genomics and molecular data sources with powerful deep learning tech...

Systems and Precision Medicine in Necrotizing Soft Tissue Infections.

Advances in experimental medicine and biology
Necrotizing soft tissue infections (NSTI) are multifactorial and characterized by dysfunctional, time dependent, highly varying hyper- to hypo-inflammatory host responses contributing to disease severity. Furthermore, host-pathogen interactions are d...

Digitizing the Pharma Neurons - A Technological Operation in Progress!

Reviews on recent clinical trials
BACKGROUND: Digitization and automation are the buzzwords in clinical research and pharma companies are investigating heavily here. Right from drug discovery to personalized medicine, digital patients and patient engagement, there is great considerat...

[Artificial intelligence-guided precision medicine in hematological disorders].

[Rinsho ketsueki] The Japanese journal of clinical hematology
Precision medicine in oncology uses genomic data to provide the right intervention in the right patients at the right time. For this purpose, next-generation sequencing (NGS) is an indispensable tool. However, further innovations are necessary, inclu...

Artificial intelligence with multi-functional machine learning platform development for better healthcare and precision medicine.

Database : the journal of biological databases and curation
Precision medicine is one of the recent and powerful developments in medical care, which has the potential to improve the traditional symptom-driven practice of medicine, allowing earlier interventions using advanced diagnostics and tailoring better ...

The Path to and Impact of Disease Recognition with AI.

IEEE pulse
The Process of rare disease identification by clinical geneticists is closely associated with the ability to correlate the phenotype of a patient with the relevant genetic syndromes. In order to perform this correlation, the phenotype has to be descr...