AIMC Topic: Precision Medicine

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Enriching patient populations in ICU trials: reducing heterogeneity through machine learning.

Current opinion in critical care
PURPOSE OF REVIEW: Despite the pivotal role of randomized controlled trials (RCTs) in critical care research, many have failed to demonstrate significant benefits, particularly in nutrition interventions. This review highlights how patient heterogene...

Harnessing an Artificial Intelligence-Based Large Language Model With Personal Health Record Capability for Personalized Information Support in Postsurgery Myocardial Infarction: Descriptive Qualitative Study.

Journal of medical Internet research
BACKGROUND: Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. Although postsurgical cardiac interventions have improved survival rates, effective management during recovery remains challenging. Traditional infor...

Artificial intelligence entering the pathology arena in oncology: current applications and future perspectives.

Annals of oncology : official journal of the European Society for Medical Oncology
BACKGROUND: Artificial intelligence (AI) is rapidly transforming the fields of pathology and oncology, offering novel opportunities for advancing diagnosis, prognosis, and treatment of cancer.

B lymphocyte subset-based stratification in primary Sjögren's syndrome: implications for lymphoma risk and personalized treatment.

Clinical rheumatology
OBJECTIVE: This study aimed to perform a detailed stratification analysis of B lymphocyte subsets in patients with primary Sjögren's syndrome (pSS) and to investigate their associations with lymphoma risk, clinical phenotypes, and disease activity.

Comparative examination of the chemistry and biology of AI-driven gold NPs in Theranostics: New insights into biosensing, bioimaging, genomics, diagnostics, and therapy.

Nanomedicine : nanotechnology, biology, and medicine
Integrating artificial intelligence (AI) with nanomedicine is transforming Theranostics, driving advances in biosensing, bioimaging, genomics, diagnostics, and treatment. This review highlights the latest advancements in AI-driven nanomedicine, focus...

Current and Emerging Precision Therapies for Developmental and Epileptic Encephalopathies.

Pediatric neurology
Developmental and epileptic encephalopathies (DEEs) are severe neurological disorders characterized by childhood-onset seizures and significant developmental impairments. Seizures are often refractory to treatment with traditional antiseizure medicat...

Role of artificial intelligence in advancing immunology.

Immunologic research
Artificial intelligence (AI) has revolutionized various biomedical fields, particularly immunology, by enhancing vaccine development, immunotherapies, and allergy treatments. AI helps identify potential vaccine candidates and predict how the body rea...

Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.

American journal of otolaryngology
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...

Decoding the crossroads of aging and cancer through single-cell analysis: Implications for precision oncology.

International journal of cancer
Single-cell analysis is a transformative approach to understanding cellular heterogeneity in aging and cancer, interconnected processes driven by mechanisms like senescence and immune modulation. This review explores how aging influences cancer initi...

Precision Strike Strategy for Liver Diseases Trilogy with Xiao-Chai-Hu Decoction: A Meta-Analysis with Machine Learning.

Phytomedicine : international journal of phytotherapy and phytopharmacology
BACKGROUND AND PURPOSE: The progression from hepatitis to liver fibrosis (LF) and ultimately to hepatic carcinoma (HCC) represents the advanced stages of various liver diseases. Currently, no universal treatment effectively addresses all three condit...