BACKGROUND AND OBJECTIVES: High-dose methylprednisolone (MP) is the global standard for treating pregnancy-associated relapses in multiple sclerosis (MS). Given that glucocorticoids cross the placenta and may interfere with fetal brain development, c...
Schizophrenia is characterized by early brain developmental abnormalities resulting in, among others, compromised communication. Rodent models, such as prenatal exposure to methylazoxymethanol acetate (MAM), help investigate schizophrenia-related def...
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing prevalence worldwide. Air pollution may be a major contributor to the rise in ASD cases. This study investigated how the risk of ASD associated with prenatal...
Childhood emotional and behavioral difficulties have a profound impact on later life outcomes, making it crucial to identify early-life risk factors that predict emotional and behavioral difficulties. However, much of the existing research has concen...
There is currently a paucity of research on the effects of early life exposure to particulate matter (PM) of various size fractions on pneumonia in preschool-aged children. We explored the connections between antenatal and postnatal exposure to atmos...
Research investigating the prenatal chemical exposome and child neurodevelopment has typically focused on a limited number of chemical exposures and controlled for sociodemographic factors and maternal mental health. Emerging machine learning approac...
BACKGROUND: Most previous research on the environmental epidemiology of childhood atopic eczema, rhinitis and wheeze is limited in the scope of risk factors studied. Our study adopted a machine learning approach to explore the role of the exposome st...
Journal of child psychology and psychiatry, and allied disciplines
Jan 29, 2024
BACKGROUND: Understanding the prenatal origins of children's psychopathology is a fundamental goal in developmental and clinical science. Recent research suggests that inflammation during pregnancy can trigger a cascade of fetal programming changes t...
Fetal Alcohol Spectrum Disorder (FASD), a wide range of physical and neurobehavioral abnormalities associated with prenatal alcohol exposure (PAE), is recognized as a significant public health concern. Advancements in the diagnosis of FASD have been ...
BACKGROUND: Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which...
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