BACKGROUND: The global burden of the opportunistic fungal disease Pneumocystis jirovecii pneumonia (PJP) remains substantial. Polymerase chain reaction (PCR) on nasopharyngeal swabs (NPS) has high specificity and may be a viable alternative to the go...
RATIONALE AND OBJECTIVES: Radiogenomics holds promise in identifying molecular alterations in nonsmall cell lung cancer (NSCLC) using imaging features. Previously, we developed a radiogenomics model to predict epidermal growth factor receptor (EGFR) ...
American journal of respiratory and critical care medicine
Sep 1, 2025
Small airway dysfunction (SAD) is a key feature of chronic obstructive pulmonary disease and might present in tobacco-exposed adults with normal spirometry. So far, the role of oscillometry-defined SAD in this population is largely unexplored. To i...
Studies in health technology and informatics
Aug 7, 2025
Chronic non-cancer pain (CNCP) is a major health concern in the United States, incurring substantial healthcare costs and frequently requiring opioid therapy in primary care. This retrospective cross-sectional study used Medicaid claims data from six...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Aug 1, 2025
BACKGROUND: The high-sensitivity C-reactive protein (Hs-CRP)-to-high-density lipoprotein cholesterol (HDL-C) ratio, which integrates insights into inflammation and lipid metabolism, serves as a comprehensive indicator. The association between this ra...
PURPOSE: The surge of treatments for COVID-19 in the second quarter of 2020 had a low prevalence of treatment and high outcome risk. Motivated by that, we conducted a simulation study comparing disease risk scores (DRS) and propensity scores (PS) usi...
The prevalence of hearing loss (HL) has emerged as an escalating public health concern globally. The objective of this study was to leverage data from the National Health and Nutritional Examination Survey (NHANES) to develop an interpretable predict...
This study systematically examined the impact of three feature selection techniques (Boruta, Extreme gradient boosting (XGBoost), and Lasso) for optimizing four machine learning models (Random forest (RF), XGBoost, Logistic regression (LR), and Suppo...
Postnatal growth faltering (PGF) significantly affects premature neonates, leading to compromised neurodevelopment and an increased risk of long-term health complications. This retrospective study at a level III NICU of a tertiary hospital analyzed...
Heavy metal exposure is acknowledged as a risk factor for poor health. However, the effect of heavy metal exposure on the prevalence of gallstones is still unknown. Therefore, we investigated the relationship between heavy metal concentrations and th...
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