AIMC Topic: Prostatic Neoplasms

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T1 and T2 MR fingerprinting measurements of prostate cancer and prostatitis correlate with deep learning-derived estimates of epithelium, lumen, and stromal composition on corresponding whole mount histopathology.

European radiology
OBJECTIVES: To explore the associations between T1 and T2 magnetic resonance fingerprinting (MRF) measurements and corresponding tissue compartment ratios (TCRs) on whole mount histopathology of prostate cancer (PCa) and prostatitis.

Time-range based sequential mining for survival prediction in prostate cancer.

Journal of biomedical informatics
BACKGROUND AND OBJECTIVE: Metastatic prostate cancer has a higher mortality rate than localized cancers. There is a need to investigate the survival outcome of metastatic prostate cancers separately. Also, the treatments undertaken by the patients af...

Cone-beam computed tomography-based radiomics in prostate cancer: a mono-institutional study.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
PURPOSE: The purpose of the reported study was to investigate the value of cone-beam computed tomography (CBCT)-based radiomics for risk stratification and prediction of biochemical relapse in prostate cancer.

Impact of rescanning and normalization on convolutional neural network performance in multi-center, whole-slide classification of prostate cancer.

Scientific reports
Algorithms can improve the objectivity and efficiency of histopathologic slide analysis. In this paper, we investigated the impact of scanning systems (scanners) and cycle-GAN-based normalization on algorithm performance, by comparing different deep ...

Accurate 3D-dose-based generation of MLC segments for robotic radiotherapy.

Physics in medicine and biology
Radiotherapy treatment planning requires accurate modeling of the delivered patient dose, including radiation scatter effects, multi-leaf collimator (MLC) leaf transmission, interleaf-leakage, etc. In fluence map optimization (FMO), a simple dose mod...

Deep Learning in Radiation Oncology Treatment Planning for Prostate Cancer: A Systematic Review.

Journal of medical systems
Radiation oncology for prostate cancer is important as it can decrease the morbidity and mortality associated with this disease. Planning for this modality of treatment is both fundamental, time-consuming and prone to human-errors, leading to potenti...

A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer.

BMC cancer
BACKGROUND: Cell-free DNA's (cfDNA) use as a biomarker in cancer is challenging due to genetic heterogeneity of malignancies and rarity of tumor-derived molecules. Here we describe and demonstrate a novel machine-learning guided panel design strategy...

[Robot-controlled MRI-guided transrectal prostate biopsy, a promising technique].

Nederlands tijdschrift voor geneeskunde
At the so-called in-bore, MRI-guided prostate biopsy, the radiologist in the MRI suite manually directs a rectal biopsy needle guide at an abnormality confirmed by a previous prostate MRI. This manual technique of taking a biopsy is time-consuming an...

Development of Convolutional Neural Networks to identify bone metastasis for prostate cancer patients in bone scintigraphy.

Annals of nuclear medicine
OBJECTIVE: The main aim of this work is to build a robust Convolutional Neural Network (CNN) algorithm that efficiently and quickly classifies bone scintigraphy images, by determining the presence or absence of prostate cancer metastasis.