AIMC Topic: Radiotherapy Dosage

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Establishing a Deep Learning Model That Integrates Pretreatment and Midtreatment Computed Tomography to Predict Treatment Response in Non-Small Cell Lung Cancer.

International journal of radiation oncology, biology, physics
PURPOSE: Patients with identical stages or similar tumor volumes can vary significantly in their responses to radiation therapy (RT) due to individual characteristics, making personalized RT for non-small cell lung cancer (NSCLC) challenging. This st...

Direct-to-Treatment Adaptive Radiation Therapy: Live Planning of Spine Metastases Using Novel Cone Beam Computed Tomography.

International journal of radiation oncology, biology, physics
PURPOSE: Cone beam computed tomography (CBCT)-based online adaptive radiation therapy is carried out using a synthetic CT (sCT) created through deformable registration between the patient-specific fan-beam CT, fan-beam computed tomography (FBCT), and...

Geometric and Dosimetric Evaluation of a RayStation Deep Learning Model for Auto-Segmentation of Organs at Risk in a Real-World Head and Neck Cancer Dataset.

Clinical oncology (Royal College of Radiologists (Great Britain))
AIMS: To assess geometric accuracy and dosimetric impact of a deep learning segmentation (DLS) model on a large, diverse dataset of head and neck cancer (HNC) patients treated with intensity-modulated proton therapy (IMPT).

Radiotherapy dose prediction using off-the-shelf segmentation networks: A feasibility study with GammaPod planning.

Medical physics
BACKGROUND: Radiotherapy requires precise, patient-specific treatment planning to achieve high-quality dose distributions that improve patient outcomes. Traditional manual planning is time-consuming and clinically impractical for performing necessary...

A knowledge-based planning model to identify fraction-reduction opportunities in brain stereotactic radiotherapy.

Journal of applied clinical medical physics
OBJECTIVE: To develop and validate a HyperArc-based RapidPlan (HARP) model for three-fraction brain stereotactic radiotherapy (SRT) plans to then use to replan previously treated five-fraction SRT plans. Demonstrating the possibility of reducing the ...

Dose prediction via deep learning to enhance treatment planning of lung radiotherapy including simultaneous integrated boost techniques.

Medical physics
BACKGROUND: Recent studies have shown deep learning techniques are able to predict three-dimensional (3D) dose distributions of radiotherapy treatment plans. However, their use in dose prediction for treatments with varied prescription doses includin...

Multi-task learning for automated contouring and dose prediction in radiotherapy.

Physics in medicine and biology
. Deep learning (DL)-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment pl...

Evaluation and failure analysis of four commercial deep learning-based autosegmentation software for abdominal organs at risk.

Journal of applied clinical medical physics
PURPOSE: Deep learning-based segmentation of organs-at-risk (OAR) is emerging to become mainstream in clinical practice because of the superior performance over atlas and model-based autocontouring methods. While several commercial deep learning-base...

Real-time adaptive proton therapy: An AI-based spatio-temporal mono-energetic dose calculation model (CC-LSTM).

Computers in biology and medicine
PURPOSE: To develop a fully AI-based dose estimation model capable of learning and estimating single pencil beam dose distributions, and to verify its performance by testing the model's generalizability on unseen, previously delivered treatment plans...

Deep learning-based quick MLC sequencing for MRI-guided online adaptive radiotherapy: a feasibility study for pancreatic cancer patients.

Physics in medicine and biology
One bottleneck of magnetic resonance imaging (MRI)-guided online adaptive radiotherapy is the time-consuming daily online replanning process. The current leaf sequencing method takes up to 10 min, with potential dosimetric degradation and small segme...