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Radiotherapy Planning, Computer-Assisted

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Generation of deep learning based virtual non-contrast CT using dual-layer dual-energy CT and its application to planning CT for radiotherapy.

PloS one
This paper presents a novel approach for generating virtual non-contrast planning computed tomography (VNC-pCT) images from contrast-enhanced planning CT (CE-pCT) scans using a deep learning model. Unlike previous studies, which often lacked sufficie...

Development and external validation of a multi-task feature fusion network for CTV segmentation in cervical cancer radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Accurate segmentation of the clinical target volume (CTV) is essential to deliver an effective radiation dose to tumor tissues in cervical cancer radiotherapy. Also, although automated CTV segmentation can reduce oncologists' ...

A unified deep-learning framework for enhanced patient-specific quality assurance of intensity-modulated radiation therapy plans.

Medical physics
BACKGROUND: Modern radiation therapy techniques, such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT), use complex fluence modulation strategies to achieve optimal patient dose distribution. Ensuring their ...

Performance of recurrent neural networks with Monte Carlo dropout for predicting pharmacokinetic parameters from dynamic contrast-enhanced magnetic resonance imaging data.

Journal of applied clinical medical physics
PURPOSE: To quantitatively evaluate the performance of two types of recurrent neural networks (RNNs), long short-term memory (LSTM) and gated recurrent units (GRU), using Monte Carlo dropout (MCD) to predict pharmacokinetic (PK) parameters from dynam...

Evaluation of AI-based auto-contouring tools in radiotherapy: A single-institution study.

Journal of applied clinical medical physics
BACKGROUND: Accurate delineation of organs at risk (OARs) is crucial yet time-consuming in the radiotherapy treatment planning workflow. Modern artificial intelligence (AI) technologies had made automation of OAR contouring feasible. This report deta...

Automatic segmentation of MRI images for brain radiotherapy planning using deep ensemble learning.

Biomedical physics & engineering express
This study aimed to develop and evaluate an efficient method to automatically segment T1- and T2-weighted brain magnetic resonance imaging (MRI) images. We specifically compared the segmentation performance of individual convolutional neural network ...

Multi-institutional Knowledge-Based (KB) plan prediction benchmark models for whole breast irradiation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To train and validate KB prediction models by merging a large multi-institutional cohort of whole breast irradiation (WBI) plans using tangential fields.

Clinical Application of Deep Learning-Assisted Needles Reconstruction in Prostate Ultrasound Brachytherapy.

International journal of radiation oncology, biology, physics
PURPOSE: High dose rate (HDR) prostate brachytherapy (BT) procedure requires image-guided needle insertion. Given that general anesthesia is often employed during the procedure, minimizing overall planning time is crucial. In this study, we explore t...

A qualitative, quantitative and dosimetric evaluation of a machine learning-based automatic segmentation method in treatment planning for gastric cancer.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To investigate the performance of a machine learning-based segmentation method for treatment planning of gastric cancer.

A prospectively deployed deep learning-enabled automated quality assurance tool for oncological palliative spine radiation therapy.

The Lancet. Digital health
BACKGROUND: Palliative spine radiation therapy is prone to treatment at the wrong anatomic level. We developed a fully automated deep learning-based spine-targeting quality assurance system (DL-SpiQA) for detecting treatment at the wrong anatomic lev...