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Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus bupivacaine hydrochloride in a porcine model.

Veterinary anaesthesia and analgesia
OBJECTIVE: To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.

Consumption of illegal home-made alcohol in Malawi: A neglected public health threat.

Alcohol (Fayetteville, N.Y.)
This study assessed the ethanol and methanol contents of homemade spirit (Kachasu) sold in Blantyre, Malawi. The likelihood of ethanol and methanol toxicity, respectively, was determined through Monte Carlo simulations using reported Kachasu intake v...

[Astragalus polysaccharide combined with cisplatin inhibits growth of recurrent tumor and down-regulats the expression of CD44, CD62P and osteopontin in tumor tissues in mice bearing Lewis lung cancer].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
Objective To investigate the effects of Astragalus polysaccharide (APS) combined with cisplatin (DDP) on the pathological morphology of recurrent tumor and the expression of metastasis-related proteins CD44, CD62P and osteopontin (OPN) following Lewi...

[Excessive fluoride increases the expression of osteocalcin in the mouse testis].

Zhonghua nan ke xue = National journal of andrology
OBJECTIVE: To observe the influence of excessive fluoride on the levels of osteocalcin and testosterone in the testis of the male mouse.

Use of a Deep Recurrent Neural Network to Reduce Wind Noise: Effects on Judged Speech Intelligibility and Sound Quality.

Trends in hearing
Despite great advances in hearing-aid technology, users still experience problems with noise in windy environments. The potential benefits of using a deep recurrent neural network (RNN) for reducing wind noise were assessed. The RNN was trained using...

Standard errors and confidence intervals for variable importance in random forest regression, classification, and survival.

Statistics in medicine
Random forests are a popular nonparametric tree ensemble procedure with broad applications to data analysis. While its widespread popularity stems from its prediction performance, an equally important feature is that it provides a fully nonparametric...

A systematic exploration of [Formula: see text] cutoff ranges in machine learning models for protein mutation stability prediction.

Journal of bioinformatics and computational biology
Discerning how a mutation affects the stability of a protein is central to the study of a wide range of diseases. Mutagenesis experiments on physical proteins provide precise insights about the effects of amino acid substitutions, but such studies ar...

relSCAN - A system for extracting chemical-induced disease relation from biomedical literature.

Journal of biomedical informatics
This paper proposes an effective and robust approach for Chemical-Induced Disease (CID) relation extraction from PubMed articles. The study was performed on the Chemical Disease Relation (CDR) task of BioCreative V track-3 corpus. The proposed system...

Large-scale Exploration of Neuronal Morphologies Using Deep Learning and Augmented Reality.

Neuroinformatics
Recently released large-scale neuron morphological data has greatly facilitated the research in neuroinformatics. However, the sheer volume and complexity of these data pose significant challenges for efficient and accurate neuron exploration. In thi...

Small-Group Technology-Assisted Instruction: Virtual Teacher and Robot Peer for Individuals with Autism Spectrum Disorder.

Journal of autism and developmental disorders
The authors combined virtual reality technology and social robotics to develop a tutoring system that resembled a small-group arrangement. This tutoring system featured a virtual teacher instructing sight words, and included a humanoid robot emulatin...