AIMC Topic: Rats
Clear Filters Showing 381 to 390 of 609 articles
A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury.
Brain injury
Dec 28, 2017
BACKGROUND: Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke, only a single study has evaluated VILIP-1 as a biomarker of traumatic brain injury (TBI). ...
ALE: automated label extraction from GEO metadata.
BMC bioinformatics
Dec 28, 2017
BACKGROUND: NCBI's Gene Expression Omnibus (GEO) is a rich community resource containing millions of gene expression experiments from human, mouse, rat, and other model organisms. However, information about each experiment (metadata) is in the format...
Quantification and pharmacokinetics of alpinetin in rat plasma by UHPLC-MS/MS using protein precipitation coupled with dilution approach to eliminate matrix effects.
Journal of pharmaceutical and biomedical analysis
Dec 27, 2017
Alpinetin, a bioactive flavonoid, has attracted great attention due to its diverse therapeutic effects, namely anti-oxidant, anti-tumor and anti-inflammatory effects with low systemic toxicity. Various determination methods have been developed in qua...
Cupuaçu extract reduces nitrosative stress and modulates inflammatory mediators in the kidneys of experimental diabetes.
Clinical nutrition (Edinburgh, Scotland)
Dec 26, 2017
BACKGROUND & AIMS: We have previously reported an increased nitrosative stress in the kidneys of diabetic animals, which was reduced by an antioxidant probiotic. The present study evaluated whether the extract of cupuaçu (EC), an antioxidant compound...
Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dec 26, 2017
Chemical composition and antioxidative, genotoxic and cytotoxic potential of essential oil (EO) and post-distillation waste (PDW) of Serbian Juniperus communis L. var. saxatilis Pall. was studied in human lung carcinoma (A549) and normal lung fibrobl...
Antioxidants
Plant Extracts
Rats
Apoptosis
Cell Line
Antineoplastic Agents, Phytogenic
Chromatography, Liquid
Drug Screening Assays, Antitumor
Tandem Mass Spectrometry
Humans
Doxorubicin
Gas Chromatography-Mass Spectrometry
Female
Mutagens
Animals
Cell Division
Male
G2 Phase
Cell Line, Tumor
Juniperus
Gas chromatography-mass spectrometry metabolomic study of lipopolysaccharides toxicity on rat basophilic leukemia cells.
Chemico-biological interactions
Dec 22, 2017
Lipopolysaccharide (LPS) can lead to uncontrollable cytokine production, fatal sepsis syndrome and depression/multiple organ failure, as pathophysiologic demonstration. Various toxic effects of LPS have been extensively reported, mainly on the toxici...
Unsupervised Network Analysis of the Plastic Supraoptic Nucleus Transcriptome Predicts Caprin2 Regulatory Interactions.
eNeuro
Dec 21, 2017
The supraoptic nucleus (SON) is a group of neurons in the hypothalamus responsible for the synthesis and secretion of the peptide hormones vasopressin and oxytocin. Following physiological cues, such as dehydration, salt-loading and lactation, the SO...
Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.
Scientific reports
Dec 20, 2017
The adverse effects of Polygonum (P.) multiflorum, including abnormal bilirubin metabolism, are a serious public health issue. As uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) is the only enzyme responsible for bilirubin metabolism, ...
ω-3 Fatty Acid Synergized Novel Nanoemulsifying System for Rosuvastatin Delivery: In Vitro and In Vivo Evaluation.
AAPS PharmSciTech
Dec 19, 2017
The present study was undertaken to improve rosuvastatin (RSV) bioavailability and pharmacological response through formation of SNES using Perilla frutescens oil as lipid carrier. The composition of oil was estimated by fatty acid methyl ester (FAME...
Effects of docosahexaenoic acid on locomotor activity in ethanol-treated HIV-1 transgenic rats.
Journal of neurovirology
Dec 19, 2017
Binge drinking affects the onset and progression of human immunodeficiency virus (HIV)-associated neurological disorders. The HIV-1 transgenic (HIV-1Tg) rat was created with a gag- and pol-deleted HIV-1 viral genome to mimic HIV-infected patients rec...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31137
- Neural Networks, Computer 29769
- Algorithms 26908
- Deep Learning 26418
- Artificial Intelligence 24354
- Robotics 13322
- Image Processing, Computer-Assisted 9552
- Retrospective Studies 9136
- Magnetic Resonance Imaging 6198
- Reproducibility of Results 5602
- Tomography, X-Ray Computed 4778
- Support Vector Machine 4695
- Computational Biology 4246
- Brain 4056
- Computer Simulation 3887
Recent Journals
- Scientific reports 6082
- Sensors (Basel, Switzerland) 4794
- PloS one 4044
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1868
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1137
- Journal of chemical information and modeling 1006
- Nature communications 959
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 829