The Journal of dermatological treatment
Dec 1, 2025
BACKGROUND: Identifying the risk of psoriasis relapse after discontinuing biologics can help optimize treatment strategies, potentially reducing relapse rates and alleviating the burden of disease management.
Accumulating real-world (RW) evidence of axicabtagene ciloleucel (axi-cel) has demonstrated comparable performance to that of pivotal trials. However, ∼57% of patients eventually relapse, with most requiring additional therapies. Being able to identi...
BACKGROUND: Substance abuse has become a serious public health problem worldwide, and finding effective prevention and treatment strategies is undoubtedly an urgent need. This study addresses the risk factors that lead to relapse behaviors among subs...
BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS characterized by a heterogeneous disease trajectory, highlighting the need for biomarkers to predict disease activity. Current disease-monitorin...
Clinical and experimental dental research
Aug 1, 2025
OBJECTIVES: Odontogenic keratocysts (OKCs) are challenging due to their aggressiveness and high recurrence rates, complicating decision-making for clinicians and pathologists. Despite efforts to identify predictive characteristics, management remains...
BACKGROUND: Endoscopic balloon dilation (EBD) is recognized as a minimally invasive and effective procedure for managing intestinal stenosis in patients with Crohn's disease (CD). It offers an alternative to surgery and has been shown to improve the ...
BACKGROUND: Obesity is a risk factor for diverticulitis. However, it remains unclear whether visceral fat area, a more precise measurement of abdominal fat, is associated with the risk of diverticulitis.
BACKGROUND: Structural remodeling of the left atrial appendage (LAA) is characteristic of atrial fibrillation (AF), and LAA morphology impacts radiofrequency catheter ablation (RFCA) outcomes. In this study, we aimed to develop and validate a predict...
European journal of pain (London, England)
Mar 1, 2025
BACKGROUND: Recurrence is common in chronic low back pain (CLBP). However, predicting the recurrence risk remains a challenge. The aim is to develop and validate a machine learning tool to predict the recurrence risk in patients with CLBP by using mu...
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