BACKGROUND AND PURPOSE: We aimed to externally validate machine learning models developed in Norway by evaluating their predictive outcome of disability and pain 12 months after lumbar disc herniation surgery in a Swedish and Danish cohort.
BACKGROUND AND PURPOSE: Treatment-related shared decision-making (SDM) in older adults with hip fractures is complex due to the need to balance patient-specific factors such as life goals, frailty, and surgical risks. It includes considerations such...
European journal of cancer (Oxford, England : 1990)
Jul 5, 2025
BACKGROUND: Cancer recurrence and progression, once seen as markers of poor prognosis, are now considered manageable aspects of long-term care. Advances in treatment have extended survival, emphasizing the need for representative epidemiological info...
OBJECTIVE: To develop models to predict opportunities for improvement in trauma care and compare the performance of these models to the currently used audit filters.
BACKGROUND: Internet-delivered cognitive behavioural therapy (ICBT) is an effective and accessible treatment for mild to moderate depression and anxiety disorders. However, up to 50% of patients do not achieve sufficient symptom relief. Identifying p...
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.
Journal of neurodevelopmental disorders
Apr 30, 2025
BACKGROUND: Functional biomarkers in neurodevelopmental disorders, such as verbal and ambulatory abilities, are essential for clinical care and research activities. Treatment planning, intervention monitoring, and identifying comorbid conditions in i...
Computer methods and programs in biomedicine
Apr 24, 2025
OBJECTIVES: Despite substantial advancements in both treatment and prevention, colorectal cancer continues to be a leading cause of global morbidity and mortality. This study investigated the potential of using demographics and prescribed drug inform...
INTRODUCTION: There is currently no comprehensive Amyotrophic Lateral Sclerosis (ALS) patient database in Singapore comparable to those available in Europe and the United States. We established the Singapore ALS registry (SingALS) to draw meaningful ...
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