BACKGROUND: Microsatellite instability (MSI) has emerged as a predictive biomarker for immunotherapy response in various cancers, but its role in non-small cell lung cancer (NSCLC) is not fully understood.
BACKGROUND: Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants and therapeutic vulnerabilities remain poorly characterized.
BACKGROUND: Ttyrosine kinase inhibitors (TKIs) represent the standard first-line treatment for patients with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma. However, not all patients with EGFR mutations respond to TKIs. This study...
Cancer imaging : the official publication of the International Cancer Imaging Society
40301906
BACKGROUND: The appropriate ligation level of the inferior mesenteric artery (IMA) in left-sided colorectal cancer (CRC) surgery is debated, with metastasis in No. 253 lymph node (No. 253 LN) being a key determining factor. This study aimed to develo...
PURPOSE: This study is aimed to develop and validate a machine learning model, which combined radiomics and clinical characteristics to predicting the definitive chemoradiotherapy (dCRT) treatment response in esophageal squamous cell carcinoma (ESCC)...
BACKGROUND: To assess the effect of the combination of deep learning reconstruction (DLR) and time-resolved maximum intensity projection (tMIP) or time-resolved average (tAve) post-processing method on image quality of CTA derived from low-dose cereb...
BACKGROUND: T2-weighted images are a critical component of prostate magnetic resonance imaging (MRI), and it would be useful to automatically assess image quality (IQ) on a patient-specific basis without radiologist oversight.
Accurate prediction of post-treatment visual acuity in macular edema secondary to retinal vein occlusion (RVO-ME) is critical for optimizing anti-VEGF therapy and improving clinical outcomes. While machine learning (ML) has shown promise in ophthalmi...
Gliomas are the most common primary tumors of the central nervous system, and advances in genetics and molecular medicine have significantly transformed their classification and treatment. This study aims to predict the IDH1 genotype in gliomas using...
Background Precise assessment of myocardial ischemia burden and cardiovascular risk stratification based on dynamic CT myocardial perfusion imaging (MPI) is lacking. Purpose To develop and validate a deep learning (DL) model for automated quantificat...