BACKGROUND: Sepsis is a significant cause of mortality in-hospital, especially in ICU patients. Early prediction of sepsis is essential, as prompt and appropriate treatment can improve survival outcomes. Machine learning methods are flexible predicti...
To greatly expand the druggable genome, fast and accurate predictions of cryptic sites for small molecules binding in target proteins are in high demand. In this study, we have developed a fast and simple conformational sampling scheme guided by norm...
OBJECTIVE: To develop and evaluate a multi-path synergic fusion (MSF) deep neural network model for breast mass classification using digital breast tomosynthesis (DBT).
Physical and engineering sciences in medicine
Dec 4, 2020
The highly contagious nature of Coronavirus disease 2019 (Covid-19) resulted in a global pandemic. Due to the relatively slow and taxing nature of conventional testing for Covid-19, a faster method needs to be in place. The current researches have su...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Deep learning methods for diabetic retinopathy (DR) diagnosis are usually criticized as being lack of interpretability in the diagnostic result, thus limiting their application in clinic. Simultaneous prediction of DR related features during the DR s...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Automated retinal vessel segmentation is among the most significant application and research topics in ophthalmologic image analysis. Deep learning based retinal vessel segmentation models have attracted much attention in the recent years. However, c...
BACKGROUND: Accurate prediction of thyroidectomy complications is necessary to inform treatment decisions. Ensemble machine learning provides one approach to improve prediction.
Visual field assessment is recognized as the important criterion of glaucomatous damage judgement; however, it can show large test-retest variability. We developed a deep learning (DL) algorithm that quantitatively predicts mean deviation (MD) of sta...
BACKGROUND: Conventional diagnosis of COVID-19 with reverse transcription polymerase chain reaction (RT-PCR) testing (hereafter, PCR) is associated with prolonged time to diagnosis and significant costs to run the test. The SARS-CoV-2 virus might lea...
INTRODUCTION: Early detection and intervention of atrial fibrillation (AF) is a cornerstone for effective treatment and prevention of mortality. Diverse deep learning models (DLMs) have been developed, but they could not be applied in clinical practi...
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