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Deep-learning approach with convolutional neural network for classification of maximum intensity projections of dynamic contrast-enhanced breast magnetic resonance imaging.

Magnetic resonance imaging
PURPOSE: We aimed to evaluate deep learning approach with convolutional neural networks (CNNs) to discriminate between benign and malignant lesions on maximum intensity projections of dynamic contrast-enhanced breast magnetic resonance imaging (MRI).

Development and evaluation of an artificial intelligence system for COVID-19 diagnosis.

Nature communications
Early detection of COVID-19 based on chest CT enables timely treatment of patients and helps control the spread of the disease. We proposed an artificial intelligence (AI) system for rapid COVID-19 detection and performed extensive statistical analys...

Identification of exacerbation risk in patients with liver dysfunction using machine learning algorithms.

PloS one
The prediction of the liver failure (LF) and its proper diagnosis would lead to a reduction in the complications of the disease and prevents the progress of the disease. To improve the treatment of LF patients and reduce the cost of treatment, we bui...

MRI-based machine learning radiomics can predict HER2 expression level and pathologic response after neoadjuvant therapy in HER2 overexpressing breast cancer.

EBioMedicine
BACKGROUND: To use clinical and MRI radiomic features coupled with machine learning to assess HER2 expression level and predict pathologic response (pCR) in HER2 overexpressing breast cancer patients receiving neoadjuvant chemotherapy (NAC).

DeepACTION: A deep learning-based method for predicting novel drug-target interactions.

Analytical biochemistry
Drug-target interactions (DTIs) play a key role in drug development and discovery processes. Wet lab prediction of DTIs is time-consuming, expensive, and tedious. Fortunately, computational approaches can identify new interactions (drug-target pairs)...

Clinical Predictive Models for COVID-19: Systematic Study.

Journal of medical Internet research
BACKGROUND: COVID-19 is a rapidly emerging respiratory disease caused by SARS-CoV-2. Due to the rapid human-to-human transmission of SARS-CoV-2, many health care systems are at risk of exceeding their health care capacities, in particular in terms of...

Sampling methods and feature selection for mortality prediction with neural networks.

Journal of biomedical informatics
Along with digitization, automatic data-driven decision support systems become increasingly popular. Mortality prediction is a vital part of that decision process. With more data available, sophisticated machine learning models like (Artificial) Neur...

Deep neural network improves the estimation of polygenic risk scores for breast cancer.

Journal of human genetics
Polygenic risk scores (PRS) estimate the genetic risk of an individual for a complex disease based on many genetic variants across the whole genome. In this study, we compared a series of computational models for estimation of breast cancer PRS. A de...

Comparison of Chest Radiograph Interpretations by Artificial Intelligence Algorithm vs Radiology Residents.

JAMA network open
IMPORTANCE: Chest radiography is the most common diagnostic imaging examination performed in emergency departments (EDs). Augmenting clinicians with automated preliminary read assistants could help expedite their workflows, improve accuracy, and redu...