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Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Extranodal extension (ENE) is a well-established poor prognosticator and an indication for adjuvant treatment escalation in patients with head and neck squamous cell carcinoma (HNSCC). Identification of ENE on pretreatment imaging represents...

Identifying bladder rupture following traumatic pelvic fracture: A machine learning approach.

Injury
INTRODUCTION: Bladder rupture following blunt pelvic trauma is rare though can have significant sequelae. We sought to determine whether machine learning could help predict the presence of bladder injury using certain factors at the time of presentat...

Convolutional Neural Network Detection of Axillary Lymph Node Metastasis Using Standard Clinical Breast MRI.

Clinical breast cancer
BACKGROUND: Axillary lymph node status is important for breast cancer staging and treatment planning as the majority of breast cancer metastasis spreads through the axillary lymph nodes. There is currently no reliable noninvasive imaging method to de...

Comparison of Walking Protocols and Gait Assessment Systems for Machine Learning-Based Classification of Parkinson's Disease.

Sensors (Basel, Switzerland)
Early diagnosis of Parkinson's diseases (PD) is challenging; applying machine learning (ML) models to gait characteristics may support the classification process. Comparing performance of ML models used in various studies can be problematic due to di...

Machine learning approach to single nucleotide polymorphism-based asthma prediction.

PloS one
Machine learning (ML) is poised as a transformational approach uniquely positioned to discover the hidden biological interactions for better prediction and diagnosis of complex diseases. In this work, we integrated ML-based models for feature selecti...

Multi-view ensemble learning with empirical kernel for heart failure mortality prediction.

International journal for numerical methods in biomedical engineering
Heart failure (HF) refers to the heart's inability to pump sufficient blood to maintain the body's needs, which has a very serious impact on human health. In recent years, the prevalence of HF has remained high. This paper proposes a multi-view ensem...

A hybrid self-attention deep learning framework for multivariate sleep stage classification.

BMC bioinformatics
BACKGROUND: Sleep is a complex and dynamic biological process characterized by different sleep patterns. Comprehensive sleep monitoring and analysis using multivariate polysomnography (PSG) records has achieved significant efforts to prevent sleep-re...

Multimodal deep representation learning for protein interaction identification and protein family classification.

BMC bioinformatics
BACKGROUND: Protein-protein interactions(PPIs) engage in dynamic pathological and biological procedures constantly in our life. Thus, it is crucial to comprehend the PPIs thoroughly such that we are able to illuminate the disease occurrence, achieve ...

DeepEP: a deep learning framework for identifying essential proteins.

BMC bioinformatics
BACKGROUND: Essential proteins are crucial for cellular life and thus, identification of essential proteins is an important topic and a challenging problem for researchers. Recently lots of computational approaches have been proposed to handle this p...