Single-cell microscopy image analysis has proved invaluable in protein subcellular localization for inferring gene/protein function. Fluorescent-tagged proteins across cellular compartments are tracked and imaged in response to genetic or environment...
Exploratory Landscape Analysis provides sample-based methods to calculate features of black-box optimization problems in a quantitative and measurable way. Many problem features have been proposed in the literature in an attempt to provide insights i...
IEEE transactions on neural networks and learning systems
Oct 9, 2018
The positive-unlabeled (PU) classification is a common scenario in real-world applications such as healthcare, text classification, and bioinformatics, in which we only observe a few samples labeled as "positive" together with a large volume of "unla...
Individualized behavioral/cognitive prediction using machine learning (ML) regression approaches is becoming increasingly applied. The specific ML regression algorithm and sample size are two key factors that non-trivially influence prediction accura...
International journal of chronic obstructive pulmonary disease
May 28, 2018
PURPOSE: The purposes of this study were development and validation of an expert system (ES) aimed at supporting the diagnosis of chronic obstructive lung disease (COLD).
Journal of clinical monitoring and computing
May 24, 2018
Traumatically brain injured (TBI) patients are at risk from secondary insults. Arterial hypotension, critically low blood pressure, is one of the most dangerous secondary insults and is related to poor outcome in patients. The overall aim of this stu...
The international journal of medical robotics + computer assisted surgery : MRCAS
Jan 10, 2018
BACKGROUND: In image-guided robotic interventions, an error component is related to the positioning error of the manipulator. Therefore, measuring the kinematic error is required during robot development. However, no specialized measurement device ex...
OBJECTIVE: Identifying patients who may experience decreased or increased mortality risk from intensive glycemic therapy for type 2 diabetes remains an important clinical challenge. We sought to identify characteristics of patients at high cardiovasc...
Electroencephalography (EEG) is an essential component in evaluation of epilepsy. However, full-channel EEG signals recorded from 18 to 23 electrodes on the scalp is neither wearable nor computationally effective. This paper presents advantages of bo...
Biomedical researchers often encounter the large-p-small-n situations-a great number of variables are measured/recorded for only a few subjects. The authors propose a fuzzy permutation method to address the multiple testing problem for small sample s...
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