Age-related hearing loss (HL) and sarcopenia (ARS) are prevalent geriatric syndromes sharing common risk factors. This study aimed to identify shared biomarkers and elucidate convergent pathogenic mechanisms. Transcriptomic datasets were obtained fro...
BACKGROUND: Sarcopenia, defined as the progressive loss of skeletal muscle mass and function, has been associated with poor prognosis in patients with pancreatic cancer, particularly those with borderline resectable pancreatic cancer (BRPC). Although...
Journal of cachexia, sarcopenia and muscle
Aug 1, 2025
BACKGROUND: The diagnosis of malnutrition has evolved with the GLIM recommendations, which advocate for integrating phenotypic criteria, including muscle mass measurement. The GLIM framework specifically suggests using skeletal muscle index (SMI) ass...
Clinical nutrition (Edinburgh, Scotland)
Aug 1, 2025
BACKGROUND: Artificial intelligence enables automated three-dimensional (3D) volumetric body composition (BC) analysis from computed tomography (CT), opposed to single third lumbar vertebra (L3) slices alone. This study aimed to identify relationship...
Journal of cachexia, sarcopenia and muscle
Jun 1, 2025
BACKGROUND: Muscle strength is one of the key components in the diagnosis of sarcopenia. The aim of this study was to train a machine learning model to predict reference values and percentiles for handgrip strength and chair-stand test (CST), in a la...
INTRODUCTION: Sarcopenia, or the loss of muscle quality and quantity, has been associated with poor clinical outcomes in liver transplantation such as infection, increased length of stay, and increased patient mortality. Abdominal computed tomography...
BACKGROUND: This study aims to investigate the relationship between muscle activation variables assessed via ultrasound and the comprehensive assessment of geriatric patients, as well as to analyze ultrasound images to determine their correlation wit...
International journal of molecular sciences
May 7, 2025
Sarcopenia, a condition characterised by the progressive decline in skeletal muscle mass and function, presents significant challenges in geriatric healthcare. Despite advances in its management, complex etiopathogenesis and the heterogeneity of diag...
BACKGROUND: Early detection is clinically crucial for the strategic handling of sarcopenia, yet the screening process, which includes assessments of muscle mass, strength, and function, remains complex and difficult to access.
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