AIMC Topic: Sensitivity and Specificity

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Novel structural descriptors for automated colon cancer detection and grading.

Computer methods and programs in biomedicine
The histopathological examination of tissue specimens is necessary for the diagnosis and grading of colon cancer. However, the process is subjective and leads to significant inter/intra observer variation in diagnosis as it mainly relies on the visua...

Local configuration pattern features for age-related macular degeneration characterization and classification.

Computers in biology and medicine
Age-related Macular Degeneration (AMD) is an irreversible and chronic medical condition characterized by drusen, Choroidal Neovascularization (CNV) and Geographic Atrophy (GA). AMD is one of the major causes of visual loss among elderly people. It is...

A Markov random field approach to group-wise registration/mosaicing with application to ultrasound.

Medical image analysis
In this paper we present a group-wise non-rigid registration/mosaicing algorithm based on block-matching, which is developed within a probabilistic framework. The discrete form of its energy functional is linked to a Markov Random Field (MRF) contain...

Control of a Wheelchair in an Indoor Environment Based on a Brain-Computer Interface and Automated Navigation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
The concept of controlling a wheelchair using brain signals is promising. However, the continuous control of a wheelchair based on unstable and noisy electroencephalogram signals is unreliable and generates a significant mental burden for the user. A...

Myocardial perfusion analysis in cardiac computed tomography angiographic images at rest.

Medical image analysis
Cardiac computed tomography angiography (CTA) is a non-invasive method for anatomic evaluation of coronary artery stenoses. However, CTA is prone to artifacts that reduce the diagnostic accuracy to identify stenoses. Further, CTA does not allow for d...

Combined unsupervised-supervised classification of multiparametric PET/MRI data: application to prostate cancer.

NMR in biomedicine
Multiparametric medical imaging data can be large and are often complex. Machine learning algorithms can assist in image interpretation when reliable training data exist. In most cases, however, knowledge about ground truth (e.g. histology) and thus ...

Development of a cervical cancer progress prediction tool for human papillomavirus-positive Koreans: A support vector machine-based approach.

The Journal of international medical research
OBJECTIVES: To develop a Web-based tool to draw attention to patients positive for human papillomavirus (HPV) who have a high risk of progression to cervical cancer, in order to increase compliance with follow-up examinations and facilitate good doct...

Deep sparse multi-task learning for feature selection in Alzheimer's disease diagnosis.

Brain structure & function
Recently, neuroimaging-based Alzheimer's disease (AD) or mild cognitive impairment (MCI) diagnosis has attracted researchers in the field, due to the increasing prevalence of the diseases. Unfortunately, the unfavorable high-dimensional nature of neu...

Echocardiogram enhancement using supervised manifold denoising.

Medical image analysis
This paper presents data-driven methods for echocardiogram enhancement. Existing denoising algorithms typically rely on a single noise model, and do not generalize to the composite noise sources typically found in real-world echocardiograms. Our meth...

Automated extraction and labelling of the arterial tree from whole-body MRA data.

Medical image analysis
In this work, we present a fully automated algorithm for extraction of the 3D arterial tree and labelling the tree segments from whole-body magnetic resonance angiography (WB-MRA) sequences. The algorithm developed consists of two core parts (i) 3D v...