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Artificial neural networks in tandem with molecular descriptors as predictive tools for continuous liposome manufacturing.

International journal of pharmaceutics May 18, 2021
The current study utilized an artificial neural network (ANN) to generate computational models to achieve process optimization for a previously developed continuous liposome manufacturing system. The liposome formation was based on a continuous manuf...
Software Water Particle Size Liposomes Neural Networks, Computer
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A Deep Learning Enhanced Novel Software Tool for Laryngeal Dynamics Analysis.

Journal of speech, language, and hearing research : JSLHR May 17, 2021
Purpose High-speed videoendoscopy (HSV) is an emerging, but barely used, endoscopy technique in the clinic to assess and diagnose voice disorders because of the lack of dedicated software to analyze the data. HSV allows to quantify the vocal fold osc...
Video Recording Glottis Vocal Cords Laryngoscopy Vibration Humans Phonation Larynx Software Deep Learning
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Treasuring the computational approach in medicinal plant research.

Progress in biophysics and molecular biology May 15, 2021
Medicinal plants serve as a valuable source of secondary metabolites since time immemorial. Computational Research in 21st century is giving more attention to medicinal plants for new drug design as pharmacological screening of bioactive compound was...
Artificial Intelligence Software Molecular Docking Simulation Molecular Dynamics Simulation Plants, Medicinal
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Artificial Intelligence in Action: Addressing the COVID-19 Pandemic with Natural Language Processing.

Annual review of biomedical data science May 14, 2021
The COVID-19 (coronavirus disease 2019) pandemic has had a significant impact on society, both because of the serious health effects of COVID-19 and because of public health measures implemented to slow its spread. Many of these difficulties are fund...
Emotions Knowledge Discovery Humans Pandemics Data Mining Natural Language Processing Software COVID-19 Datasets as Topic Periodicals as Topic Communication Information Storage and Retrieval
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Hierarchical progressive learning of cell identities in single-cell data.

Nature communications May 14, 2021
Supervised methods are increasingly used to identify cell populations in single-cell data. Yet, current methods are limited in their ability to learn from multiple datasets simultaneously, are hampered by the annotation of datasets at different resol...
Supervised Machine Learning Cells Computer Simulation Animals Leukocytes, Mononuclear Deep Learning Single-Cell Analysis Mice Software Databases, Factual Brain Humans
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Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.

Physics in medicine and biology May 14, 2021
Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand...
Computer Simulation Tomography, X-Ray Computed Monte Carlo Method Artificial Intelligence Software
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Diagnosis of Acute Poisoning using explainable artificial intelligence.

Computers in biology and medicine May 13, 2021
INTRODUCTION: Medical toxicology is the clinical specialty that treats the toxic effects of substances, for example, an overdose, a medication error, or a scorpion sting. The volume of toxicological knowledge and research has, as with other medical s...
Software Artificial Intelligence Reproducibility of Results Humans Machine Learning
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Drug Target Identification with Machine Learning: How to Choose Negative Examples.

International journal of molecular sciences May 12, 2021
Identification of the protein targets of hit molecules is essential in the drug discovery process. Target prediction with machine learning algorithms can help accelerate this search, limiting the number of required experiments. However, Drug-Target I...
Machine Learning Pharmaceutical Preparations Software Computational Biology Humans Support Vector Machine Drug Discovery Protein Interaction Mapping Proteins
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Accuracy of a convolutional neural network for dermatological diagnosis of tumours and skin lesions in a clinical setting.

Clinical and experimental dermatology May 11, 2021
Skin Neoplasms Diagnosis, Computer-Assisted Diagnosis, Differential Humans Neural Networks, Computer Software Skin Diseases
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Assistance from Automated ASPECTS Software Improves Reader Performance.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association May 11, 2021
PURPOSE: To compare physicians' ability to read Alberta Stroke Program Early CT Score (ASPECTS) in patients with a large vessel occlusion within 6 hours of symptom onset when assisted by a machine learning-based automatic software tool, compared with...
Machine Learning Software Prognosis Humans Aged Male Middle Aged Tomography, X-Ray Computed Female Reproducibility of Results Radiographic Image Interpretation, Computer-Assisted Observer Variation Predictive Value of Tests Automation Clinical Competence Middle Cerebral Artery Ischemic Stroke Magnetic Resonance Imaging Radiologists Carotid Artery, Internal Neurologists
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