Starch is a fundamental carbohydrate with nutritional and physicochemical properties governed by relative proportions of amylose and amylopectin. Variations in amylose-to-amylopectin ratio significantly influence starch digestibility, texture, glycem...
This study proposes a method for detecting trace quinolone antibiotics in milk using a ternary composite surface-enhanced Raman spectroscopy (SERS) substrate. It combines chemometric algorithms and deep learning models to achieve qualitative and quan...
Tilianin is a commonly used pharmaceutical ingredient with various biological activities such as antioxidant, anti-inflammatory, and anticancer, which is able to exert antitumor effects by inhibiting tumor cell proliferation, inducing apoptosis and i...
Advances in virtual staining and spatial omics have revolutionized our ability to explore cellular architecture and molecular composition with unprecedented detail. Virtual staining techniques, which rely on computational algorithms to map molecular ...
Gastric cancer is one of the most common malignant tumors of the digestive system, with a high mortality rate due to late-stage diagnosis. Current clinical diagnosis relies on endoscopic biopsy and histopathological analysis, which are highly depende...
Fed-batch fermentation has become the preferred strategy in many industrial biomanufacturing processes. However, a key challenge remains in optimizing the feeding strategy to achieve stable maximum yields. In this study, we present an online Raman sp...
Accurate preoperative diagnosis of papillary thyroid carcinoma (PTC) histological subtypes and lymph node metastasis is essential for formulating personalized treatment strategies. However, their preoperative diagnosis is challenged by the limited re...
A method to directly predict the number of nucleic acid bases in a single-stranded DNA (ssDNA) or a genomic DNA has been proposed with a combination of Raman spectroscopy and an Artificial Neural Network (ANN) algorithm. In this work, the algorithm w...
Surface-enhanced Raman spectroscopy (SERS) has emerged as a transformative analytical tool in disease diagnostics, offering unparalleled sensitivity and molecular fingerprinting capabilities. However, its clinical translation is hindered by the inher...
Measures of structural protein alignment within biological and engineered tissues are needed for improved understanding of their mechanical behavior and functionality. We advance our method of measuring protein alignment using polarized Raman spectro...
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