BACKGROUND: Antibiotic residues pose varying degrees of potential hazards to the water environment and human health due to their diverse types. Surface-enhanced Raman spectroscopy (SERS) technology can achieve rapid detection of various antibiotic re...
The bacterial surface is rich in diverse molecular features, and fully exploiting these natural recognition mechanisms provides innovative avenues for multimechanism detection of foodborne pathogens. Here, we developed a label-free, dual-modal LFIA p...
The detection of soluble arsenic in realgar and its preparations is crucial for toxicity evaluation. Therefore, surface-enhanced Raman spectroscopy (SERS) combined with machine learning was applied for the rapid detection of soluble As3+ in realgar a...
Shiga toxins-producing (STEC) are zoonotic pathogens causing severe diseases such as hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). Infections caused by STEC represent a public health concern due to the severity of the possible outcom...
Diabetes mellitus (DM), a prevalent metabolic disorder, poses significant diagnostic and therapeutic challenges, especially, in the early stage diagnosis of diabetes related complications. Accurate early stage diagnosis of diabetes and its complicati...
Regulatory T cells are a class of T lymphocytes which respond to activation signals by expanding their cell numbers, and whose culturing and expansion are of significant clinical interest. Cellular activation states are used to inform process control...
BACKGROUND: Cholangiocarcinoma (CCA) is a deadly cancer often detected late. Current diagnostic methods, such as ultrasound and invasive biopsies, have limitations; there is a critical need for a rapid, minimally invasive and effective strategy for t...
Simultaneous detection of metabolites and proteins─two chemically and functionally distinct classes of biomolecules─in complex biofluids remains a significant analytical hurdle, yet is critical for early and accurate disease diagnosis. These difficul...
Gastric cancer is a leading cause of cancer-related mortality and highlights the need for early detection of gastric cancer and Helicobacter pylori (HP) infection, which is a major risk factor. Early non-invasive and convenient diagnostic tools capab...
Prostate cancer is characterized by an immunosuppressive tumour environment. This work combines Raman spectroscopy with group-and-bases-restricted non-negative matrix factorization (GBR-NMF) and machine learning to assemble models of immune cell dens...
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