AIMC Topic: Stomach Neoplasms

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Development and validation of CT-based fusion model for preoperative prediction of invasion and lymph node metastasis in adenocarcinoma of esophagogastric junction.

BMC medical imaging
PURPOSE: In the context of precision medicine, radiomics has become a key technology in solving medical problems. For adenocarcinoma of esophagogastric junction (AEG), developing a preoperative CT-based prediction model for AEG invasion and lymph nod...

Muscle-Driven prognostication in gastric cancer: A multicenter deep learning framework integrating Iliopsoas and erector spinae radiomics for 5-Year survival prediction.

Scientific reports
This study developed a 5-year survival prediction model for gastric cancer patients by combining radiomics and deep learning, focusing on CT-based 2D and 3D features of the iliopsoas and erector spinae muscles. Retrospective data from 705 patients ac...

A hybrid multi-instance learning-based identification of gastric adenocarcinoma differentiation on whole-slide images.

Biomedical engineering online
OBJECTIVE: To investigate the potential of a hybrid multi-instance learning model (TGMIL) combining Transformer and graph attention networks for classifying gastric adenocarcinoma differentiation on whole-slide images (WSIs) without manual annotation...

Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with "double invasion" for personalized patient care.

European journal of medical research
OBJECTIVE: To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.

Time-Gated Raman Spectroscopy Combined with Deep Learning for Rapid, Label-Free Histopathological Discrimination of Gastric Cancer.

Analytical chemistry
Gastric cancer is one of the most common malignant tumors of the digestive system, with a high mortality rate due to late-stage diagnosis. Current clinical diagnosis relies on endoscopic biopsy and histopathological analysis, which are highly depende...

Interpretable deep learning for gastric cancer detection: a fusion of AI architectures and explainability analysis.

Frontiers in immunology
INTRODUCTION: The rise in cases of Gastric Cancer has increased in recent times and demands accurate and timely detection to improve patients' well-being. The traditional cancer detection techniques face issues of explainability and precision posing ...

Revealing 3D microanatomical structures of unlabeled thick cancer tissues using holotomography and virtual H&E staining.

Nature communications
In histopathology, acquiring subcellular-level three-dimensional (3D) tissue structures efficiently and without damaging the tissues during serial sectioning and staining remains a formidable challenge. We address this by integrating holotomography w...

Deciphering microbial and metabolic influences in gastrointestinal diseases-unveiling their roles inĀ gastric cancer, colorectal cancer, and inflammatory bowel disease.

Journal of translational medicine
INTRODUCTION: Gastrointestinal disorders (GIDs) affect nearly 40% of the global population, with gut microbiome-metabolome interactions playing a crucial role in gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD). This...

Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study.

Gut
BACKGROUND AND OBJECTIVE: Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, have emerged as promising diagnostic biomarkers f...