Despite its potential, the use of machine learning in safety studies had been limited. Considering machine learning's advantage in predictive accuracy, this study used a supervised learning approach to evaluate the relative importance of different co...
BACKGROUND: Social media is a useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of Adve...
IEEE journal of biomedical and health informatics
Jun 12, 2018
Predicting the protein-protein interactions (PPIs) has played an important role in many applications. Hence, a novel computational method for PPIs prediction is highly desirable. PPIs endow with protein amino acid mutation rate and two physicochemica...
BACKGROUND: Prevention of persistent pain following breast cancer surgery, via early identification of patients at high risk, is a clinical need. Supervised machine-learning was used to identify parameters that predict persistence of significant pain...
Quality control (QC) is a fundamental component of any study. Diffusion MRI has unique challenges that make manual QC particularly difficult, including a greater number of artefacts than other MR modalities and a greater volume of data. The gold stan...
OBJECTIVE: An ability to map seizure-generating brain tissue, i.e. the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted practi...
BACKGROUND: Gene-expression companion diagnostic tests, such as the Oncotype DX test, assess the risk of early stage Estrogen receptor (ER) positive (+) breast cancers, and guide clinicians in the decision of whether or not to use chemotherapy. Howev...
The widely used American Society of Anesthesiologists Physical Status (ASA PS) classification is subjective, requires manual clinician review to score, and has limited granularity. Our objective was to develop a system that automatically generates an...
IEEE transactions on neural networks and learning systems
May 28, 2018
Spiking neurons are becoming increasingly popular owing to their biological plausibility and promising computational properties. Unlike traditional rate-based neural models, spiking neurons encode information in the temporal patterns of the transmitt...
Defining subtypes of complex diseases such as cancer and stratifying patient groups with the same disease but different subtypes for targeted treatments is important for personalized and precision medicine. Approaches that incorporate multi-omic data...
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