IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jan 25, 2019
Brain-computer interfaces based on motor imagery (MI) have been widely used to support the rehabilitation of motor functions of the upper limbs rather than lower limbs. This is probably because it is more difficult to detect the brain activities of l...
BACKGROUND: BRCA1-mutated cancers exhibit deficient homologous recombination (HR) DNA repair, resulting in extensive copy number alterations and genome instability. HR deficiency can also arise in tumors without a BRCA1 mutation. Compared with other ...
Type IV secretion systems exist in a number of bacterial pathogens and are used to secrete effector proteins directly into host cells in order to change their environment making the environment hospitable for the bacteria. In recent years, several ma...
As an abundant post-transcriptional modification, dihydrouridine (D) has been found in transfer RNA (tRNA) from bacteria, eukaryotes, and archaea. Nonetheless, knowledge of the exact biochemical roles of dihydrouridine in mediating tRNA function is s...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 18, 2019
Accurately identifying DNA-binding proteins (DBPs) from protein sequence information is an important but challenging task for protein function annotations. In this paper, we establish a novel computational method, named TargetDBP, for accurately targ...
Side effects occur when excessive or low doses of analgesics are administered compared to the required amount to mediate the pain induced during surgery. It is important to accurately assess the pain level of the patient during surgery. We proposed a...
Gait classification has been widely used for children with cerebral palsy (CP) to assist with clinical decision making and to evaluate different treatment outcomes. The aim of this study was to evaluate supervised machine learning algorithms in the c...
Forensic science, medicine, and pathology
Jan 16, 2019
Single nucleotide polymorphism (SNP) profiling is an effective means of individual identification and ancestry inferences in forensic genetics. This study established a SNP panel for the simultaneous individual identification and ancestry assignment ...
Coarse-grained rules are widely used in chemistry, physics and engineering. In biology, however, such rules are less common and under-appreciated. This gap can be attributed to the difficulty in establishing general rules to encompass the immense div...
HIV-associated neurocognitive disorders (HAND) represent an important source of neurologic complications in individuals with HIV. The dynamic, often subclinical, course of HAND has rendered diagnosis, which currently depends on neuropsychometric (NP)...
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