AIMC Topic: Synaptic Transmission

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DoGNet: A deep architecture for synapse detection in multiplexed fluorescence images.

PLoS computational biology May 13, 2019
Neuronal synapses transmit electrochemical signals between cells through the coordinated action of presynaptic vesicles, ion channels, scaffolding and adapter proteins, and membrane receptors. In situ structural characterization of numerous synaptic ...
Computer Simulation Animals Image Processing, Computer-Assisted Mice Neural Networks, Computer Software Databases, Factual Synapses Cerebral Cortex Synaptic Transmission Microscopy, Fluorescence, Multiphoton Computational Biology Models, Neurological Nerve Tissue Proteins Neurons
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Memristive Imitation of Synaptic Transmission and Plasticity.

IEEE transactions on neural networks and learning systems Feb 11, 2019
In this paper, a memristive artificial neural circuit imitating the excitatory chemical synaptic transmission of biological synapse is designed. The proposed memristor-based neural circuit exhibits synaptic plasticity, one of the important neurochemi...
Imitative Behavior Humans Neural Networks, Computer Neuronal Plasticity Synaptic Transmission
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Working Memory and Decision-Making in a Frontoparietal Circuit Model.

The Journal of neuroscience : the official journal of the Society for Neuroscience Nov 7, 2017
Working memory (WM) and decision-making (DM) are fundamental cognitive functions involving a distributed interacting network of brain areas, with the posterior parietal cortex (PPC) and prefrontal cortex (PFC) at the core. However, the shared and dis...
Memory, Short-Term Connectome Synaptic Transmission Parietal Lobe Prefrontal Cortex Humans Models, Neurological Neural Networks, Computer Action Potentials Computer Simulation Decision Making
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Synaptic convergence regulates synchronization-dependent spike transfer in feedforward neural networks.

Journal of computational neuroscience Sep 12, 2017
Correlated neural activities such as synchronizations can significantly alter the characteristics of spike transfer between neural layers. However, it is not clear how this synchronization-dependent spike transfer can be affected by the structure of ...
Humans Neural Networks, Computer Neurons Synapses Nerve Net Normal Distribution Computer Simulation Animals Models, Neurological Action Potentials Synaptic Transmission
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Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.

Scientific reports Aug 8, 2017
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...
Cortical Excitability Receptors, Dopamine GABAergic Neurons Neural Inhibition Glutamic Acid Rodentia Synapses Cerebral Cortex Species Specificity Connectome Corpus Striatum gamma-Aminobutyric Acid Thalamus Synaptic Transmission Humans Neural Networks, Computer Animals Reward
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Synaptic damage underlies EEG abnormalities in postanoxic encephalopathy: A computational study.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Jul 8, 2017
OBJECTIVE: In postanoxic coma, EEG patterns indicate the severity of encephalopathy and typically evolve in time. We aim to improve the understanding of pathophysiological mechanisms underlying these EEG abnormalities.
Long-Term Potentiation Coma Hypoxia, Brain Male Middle Aged Synapses Humans Electroencephalography Heart Arrest Neural Networks, Computer Netherlands Synaptic Transmission Female Membrane Potentials Aged
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Neuronify: An Educational Simulator for Neural Circuits.

eNeuro Mar 17, 2017
Educational software (apps) can improve science education by providing an interactive way of learning about complicated topics that are hard to explain with text and static illustrations. However, few educational apps are available for simulation of ...
Synaptic Transmission Neurosciences Touch Neural Inhibition Periodicity Action Potentials Neurons Vision, Ocular Electric Stimulation Animals Neural Networks, Computer Mobile Applications Models, Neurological
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Mimicking Neurotransmitter Release in Chemical Synapses via Hysteresis Engineering in MoS Transistors.

ACS nano Mar 10, 2017
Neurotransmitter release in chemical synapses is fundamental to diverse brain functions such as motor action, learning, cognition, emotion, perception, and consciousness. Moreover, improper functioning or abnormal release of neurotransmitter is assoc...
Humans Neural Networks, Computer Molybdenum Synapses Disulfides Synaptic Transmission Neurotransmitter Agents
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Neuromorphic meets neuromechanics, part II: the role of fusimotor drive.

Journal of neural engineering Jan 17, 2017
OBJECTIVE: We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of...
Signal Processing, Computer-Assisted Models, Neurological Afferent Pathways Humans Biomimetics Muscle Spindles Action Potentials Computer Simulation Muscle Contraction Muscle, Skeletal Motor Neurons, Gamma Animals Synaptic Transmission Robotics Neuromuscular Junction
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Neuromorphic meets neuromechanics, part I: the methodology and implementation.

Journal of neural engineering Jan 13, 2017
OBJECTIVE: One goal of neuromorphic engineering is to create 'realistic' robotic systems that interact with the physical world by adopting neuromechanical principles from biology. Critical to this is the methodology to implement the spinal circuitry ...
Action Potentials Muscle, Skeletal Afferent Pathways Biomimetics Robotics Humans Muscle Spindles Muscle Contraction Signal Processing, Computer-Assisted Computer Simulation Synaptic Transmission Neuromuscular Junction Animals Motor Neurons Models, Neurological
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