AIMC Topic: Synaptic Transmission

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Working Memory and Decision-Making in a Frontoparietal Circuit Model.

The Journal of neuroscience : the official journal of the Society for Neuroscience Nov 7, 2017
Working memory (WM) and decision-making (DM) are fundamental cognitive functions involving a distributed interacting network of brain areas, with the posterior parietal cortex (PPC) and prefrontal cortex (PFC) at the core. However, the shared and dis...
Humans Neural Networks, Computer Computer Simulation Memory, Short-Term Connectome Synaptic Transmission Parietal Lobe Prefrontal Cortex Models, Neurological Action Potentials Decision Making
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Synaptic convergence regulates synchronization-dependent spike transfer in feedforward neural networks.

Journal of computational neuroscience Sep 12, 2017
Correlated neural activities such as synchronizations can significantly alter the characteristics of spike transfer between neural layers. However, it is not clear how this synchronization-dependent spike transfer can be affected by the structure of ...
Synaptic Transmission Synapses Nerve Net Normal Distribution Humans Animals Neural Networks, Computer Models, Neurological Computer Simulation Action Potentials Neurons
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Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.

Scientific reports Aug 8, 2017
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...
Humans Neural Networks, Computer Species Specificity Connectome Corpus Striatum gamma-Aminobutyric Acid Animals Reward Synapses Cerebral Cortex Receptors, Dopamine Neural Inhibition Glutamic Acid Rodentia Cortical Excitability Thalamus Synaptic Transmission GABAergic Neurons
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Synaptic damage underlies EEG abnormalities in postanoxic encephalopathy: A computational study.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Jul 8, 2017
OBJECTIVE: In postanoxic coma, EEG patterns indicate the severity of encephalopathy and typically evolve in time. We aim to improve the understanding of pathophysiological mechanisms underlying these EEG abnormalities.
Coma Hypoxia, Brain Synaptic Transmission Membrane Potentials Long-Term Potentiation Aged Male Middle Aged Electroencephalography Netherlands Synapses Heart Arrest Humans Neural Networks, Computer Female
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Neuronify: An Educational Simulator for Neural Circuits.

eNeuro Mar 17, 2017
Educational software (apps) can improve science education by providing an interactive way of learning about complicated topics that are hard to explain with text and static illustrations. However, few educational apps are available for simulation of ...
Neural Networks, Computer Synaptic Transmission Action Potentials Neurosciences Neurons Touch Animals Periodicity Vision, Ocular Neural Inhibition Mobile Applications Electric Stimulation Models, Neurological
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Mimicking Neurotransmitter Release in Chemical Synapses via Hysteresis Engineering in MoS Transistors.

ACS nano Mar 10, 2017
Neurotransmitter release in chemical synapses is fundamental to diverse brain functions such as motor action, learning, cognition, emotion, perception, and consciousness. Moreover, improper functioning or abnormal release of neurotransmitter is assoc...
Neurotransmitter Agents Humans Neural Networks, Computer Synapses Molybdenum Disulfides Synaptic Transmission
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Neuromorphic meets neuromechanics, part II: the role of fusimotor drive.

Journal of neural engineering Jan 17, 2017
OBJECTIVE: We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of...
Action Potentials Muscle, Skeletal Robotics Signal Processing, Computer-Assisted Muscle Spindles Computer Simulation Humans Biomimetics Motor Neurons, Gamma Animals Muscle Contraction Neuromuscular Junction Models, Neurological Synaptic Transmission Afferent Pathways
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Neuromorphic meets neuromechanics, part I: the methodology and implementation.

Journal of neural engineering Jan 13, 2017
OBJECTIVE: One goal of neuromorphic engineering is to create 'realistic' robotic systems that interact with the physical world by adopting neuromechanical principles from biology. Critical to this is the methodology to implement the spinal circuitry ...
Biomimetics Muscle Contraction Synaptic Transmission Motor Neurons Afferent Pathways Muscle Spindles Neuromuscular Junction Action Potentials Muscle, Skeletal Robotics Signal Processing, Computer-Assisted Computer Simulation Humans Animals Models, Neurological
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Impaired neurogenesis of the dentate gyrus is associated with pattern separation deficits: A computational study.

Journal of integrative neuroscience Sep 21, 2016
The separation of input patterns received from the entorhinal cortex (EC) by the dentate gyrus (DG) is a well-known critical step of information processing in the hippocampus. Although the role of interneurons in separation pattern efficiency of the ...
Models, Neurological Neural Networks, Computer Neurogenesis Neurons Animals Alzheimer Disease Synaptic Transmission Dentate Gyrus
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The effect of the neural activity on topological properties of growing neural networks.

Journal of integrative neuroscience Aug 10, 2016
The connectivity structure in cortical networks defines how information is transmitted and processed, and it is a source of the complex spatiotemporal patterns of network's development, and the process of creation and deletion of connections is conti...
Neural Pathways Neural Networks, Computer Synaptic Transmission Animals Neurons
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