We used an ensemble of statistical methods to build a model that predicts kidney transplant survival and identifies important predictive variables. The proposed model achieved better performance, measured by Harrell's concordance index, than the Esti...
Close monitoring of estimated glomerular filtration rate (eGFR) is important for early recognition of worsening renal function to prevent further deterioration. Safe conversion from twice-daily tacrolimus (TD-Tac) to once-daily tacrolimus (OD-Tac) ha...
Accurate prediction of graft survival after kidney transplant is limited by the complexity and heterogeneity of risk factors influencing allograft survival. In this study, we applied machine learning methods, in combination with survival statistics, ...
Tacrolimus has a narrow therapeutic window and considerable variability in clinical use. Our goal was to compare the performance of multiple linear regression (MLR) and eight machine learning techniques in pharmacogenetic algorithm-based prediction o...
Simulated allocation models (SAMs) are used to evaluate organ allocation policies. An important component of SAMs is a module that decides whether each potential recipient will accept an offered organ. The objective of this study was to develop and t...
Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for older adults with hematologic malignancies. Concerns on nonrelapse mortality (NRM) in older adults limit allo-HCT utilization. We executed a prospective, observation...
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2025
OBJECTIVES: Primary graft dysfunction (PGD) is an essential outcome after the heart transplant, which causes severe complications and symptoms for recipients. The in advance prediction of PGD can help the transplant physician better manage the risks ...
INTRODUCTION: Sarcopenia, or the loss of muscle quality and quantity, has been associated with poor clinical outcomes in liver transplantation such as infection, increased length of stay, and increased patient mortality. Abdominal computed tomography...
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...
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