AIMC Topic: Vitamin D Deficiency

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Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition Nov 15, 2019
Genome Wide Association Studies (GWAS) have evaluated several genes related to vitamin D synthesis, metabolism and transport. They have proposed a genetic basis for low levels of vitamin D in the blood. The current study aims to investigate the rela...
Vitamin D Deficiency Vitamin D-Binding Protein Genome-Wide Association Study Iran Genetic Predisposition to Disease Humans Polymorphism, Single Nucleotide Cholestanetriol 26-Monooxygenase Female Genotype Cytochrome P-450 Enzyme System Male Vitamin D Cytochrome P450 Family 2 Case-Control Studies Adolescent
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Directional Relationship Between Vitamin D Status and Prediabetes: A New Approach from Artificial Neural Network in a Cohort of Workers with Overweight-Obesity.

Journal of the American College of Nutrition Apr 25, 2019
Despite the increasing literature on the association of diabetes with inflammation, cardiovascular risk, and vitamin D (25(OH)D) concentrations, strong evidence on the direction of causality among these factors is still lacking. This gap could be ad...
Humans Neural Networks, Computer Retrospective Studies Cohort Studies Overweight Vitamin D Vitamin D Deficiency Data Mining Prediabetic State Female Aged Adult Male Middle Aged
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Vitamin D in the ICU: More sun for critically ill adult patients?

Nutrition (Burbank, Los Angeles County, Calif.) Nov 16, 2018
Critical illness in patients is characterized by systemic inflammation and oxidative stress. Vitamin D has a myriad of biological functions relevant to this population, including immunomodulation by the alteration of cytokine production and nuclear f...
Nutrition Therapy Humans Hospital Mortality Critical Illness Vitamin D Intensive Care Units Vitamin D Deficiency Adult Dietary Supplements Vitamins
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Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

Nutrition (Burbank, Los Angeles County, Calif.) Oct 24, 2018
OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum...
Intensive Care Units Female Aged Adult Cross-Sectional Studies Respiration, Artificial Comorbidity Severity of Illness Index Male Middle Aged Neoplasms Humans Organ Dysfunction Scores Prognosis Patient Admission Critical Illness Acute Disease Respiratory Insufficiency APACHE Infections Liver Failure Time Factors Hospital Mortality Vitamin D Vitamin D Deficiency C-Reactive Protein
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Effect of combined vitamin D administration plus dietary intervention on oxidative stress markers in patients with metabolic syndrome: A pilot randomized study.

Clinical nutrition ESPEN Oct 24, 2018
BACKGROUND: Metabolic syndrome (MetS) patients can have low 25-hydroxyvitamin D 25(OH)VitD levels, which may be associated with increased oxidative stress. There is little data on the effect of 25(OH)VitD administration plus dietary intervention on o...
Aryldialkylphosphatase Oxidative Stress Vitamin D Vitamin D Deficiency Metabolic Syndrome Dietary Supplements Lipoproteins, LDL Combined Modality Therapy Carboxylic Ester Hydrolases Greece Dinoprost Female Adult Male Middle Aged Pilot Projects Humans Biomarkers
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Non-surgical management of primary hyperparathyroidism.

Best practice & research. Clinical endocrinology & metabolism Sep 28, 2018
The purpose of this chapter is to discuss the options available for patients with primary hyperparathyrodism (PHPT) not undergoing parathyroidectomy (PTx). Adequate hydration should be recommended in all patients. Calcium intake should not be restric...
Cinacalcet Hyperparathyroidism, Primary Pregnancy Complications Humans Pregnancy Female Parathyroid Hormone Vitamin D Deficiency Hypercalcemia Fluid Therapy Parathyroidectomy Calcium
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Serum vitamin D deficiency and vitamin D receptor gene polymorphism are associated with increased risk of cardiovascular disease in a Chinese rural population.

Nutrition research (New York, N.Y.) Sep 13, 2018
Several studies have reported a conflicting association between vitamin D deficiency, vitamin D receptor (VDR) polymorphism, and the risk of cardiovascular disease (CVD). We hypothesized that serum 25(OH)D concentrations and single nucleotide polymor...
Gene Frequency Triglycerides Receptors, Calcitriol Vitamin D Deficiency Humans Alleles Biomarkers Asian People Female Haplotypes Aged Blood Glucose Adult Polymorphism, Single Nucleotide Logistic Models Male Genotype Rural Population Cardiovascular Diseases Vitamin D Middle Aged China
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Association between vitamin D deficiency and insulin resistance markers in euthyroid non-diabetic individuals.

Diabetes & metabolic syndrome Sep 8, 2018
AIM: To evaluate the association between vitamin D deficiency and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in euthyroid non-diabetic individuals.
Adult Cross-Sectional Studies Male Prevalence Thyroid Gland Humans Biomarkers Prognosis Female Insulin Resistance Vitamin D Deficiency Follow-Up Studies Peru Hyperinsulinism
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The effect of vitamin D supplementation on insulin resistance, visceral fat and adiponectin in vitamin D deficient women with polycystic ovary syndrome: a randomized placebo-controlled trial.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Dec 22, 2017
INTRODUCTION: Low plasma 25-hydroxy-vitamin D (25OHD) is associated with polycystic ovary syndrome (PCOS). Vitamin D deficiency may contribute to the development of insulin resistance, visceral fat and low level of adiponectin which are common featur...
Humans Female Young Adult Adult Blood Glucose Insulin Polycystic Ovary Syndrome Adiponectin Cholecalciferol Insulin Resistance Intra-Abdominal Fat Hormone Replacement Therapy Treatment Outcome Vitamin D Deficiency Dietary Supplements
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Vitamin D deficiency and supplementation in patients with aggressive B-cell lymphomas treated with immunochemotherapy.

Cancer medicine Dec 22, 2017
Vitamin D deficiency has been reported to be a negative prognostic factor in elderly patients with aggressive B-cell lymphomas. In vitro data suggest that vitamin D supplementation may enhance rituximab-mediated cytotoxicity. We prospectively assesse...
Rituximab Vincristine Disease-Free Survival Doxorubicin Cyclophosphamide Cholecalciferol Prednisone Female Aged Lymphoma, Large B-Cell, Diffuse Male Middle Aged Vitamin D Vitamin D Deficiency Dietary Supplements Humans Immunotherapy Antineoplastic Combined Chemotherapy Protocols Treatment Outcome
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