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A deep-learning-based workflow to assess taxonomic affinity of hominid teeth with a test on discriminating Pongo and Homo upper molars.

American journal of physical anthropology
OBJECTIVES: Convolutional neural network (CNN) is a state-of-art deep learning (DL) method with superior performance in image classification. Here, a CNN-based workflow is proposed to discriminate hominid teeth. Our hope is that this method could hel...

Generative Deep Learning in Digital Pathology Workflows.

The American journal of pathology
Many modern histopathology laboratories are in the process of digitizing their workflows. Digitization of tissue images has made it feasible to research the augmentation or automation of clinical reporting and diagnosis. The application of modern com...

Safety-driven design of machine learning for sepsis treatment.

Journal of biomedical informatics
Machine learning (ML) has the potential to bring significant clinical benefits. However, there are patient safety challenges in introducing ML in complex healthcare settings and in assuring the technology to the satisfaction of the different regulato...

Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox.

Genome biology
The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are prevailing i...

Performance of an artificial intelligence tool with real-time clinical workflow integration - Detection of intracranial hemorrhage and pulmonary embolism.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Ethical evaluation of artificial intelligence applications in radiotherapy using the Four Topics Approach.

Artificial intelligence in medicine
Artificial Intelligence is the capability of a machine to imitate intelligent human behavior. An important impact can be expected from Artificial Intelligence throughout the workflow of radiotherapy (such as automated organ segmentation, treatment pl...

A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus.

Molecular diversity
Dipeptidyl peptidase-4 (DPP4) is highly participated in regulating diabetes mellitus (DM), and inhibitors of DPP4 may act as potential DM drugs. Therefore, we performed a novel artificial intelligence (AI) protocol to screen and validate the potentia...

seqQscorer: automated quality control of next-generation sequencing data using machine learning.

Genome biology
Controlling quality of next-generation sequencing (NGS) data files is a necessary but complex task. To address this problem, we statistically characterize common NGS quality features and develop a novel quality control procedure involving tree-based ...

DeepAlign, a 3D alignment method based on regionalized deep learning for Cryo-EM.

Journal of structural biology
Cryo Electron Microscopy (Cryo-EM) is currently one of the main tools to reveal the structural information of biological specimens at high resolution. Despite the great development of the techniques involved to solve the biological structures with Cr...